[4] Jordan M B, Hildeman D, Kappler J, et al. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder[J]. Blood, 2004,104(3):735-743. [5] 刘炜, 赵利敏, 王天有. ...
[4] Jordan MB, Hildeman D, Kappler J, et al. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+T cells and interferon gamma are essential for the disorder [J]. Blood, 2004, 104(3): 735-743. [5] Locatelli F, Jordan MB, ...
[4] Jordan MB, Hildeman D, Kappler J, et al. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+T cells and interferon gamma are essential for the disorder [J]. Blood, 2004, 104(3): 735-743. [5] Locatelli F, Jordan MB, Allen C, et al. Emapalumab in Children with...
噬血细胞性淋巴组织细胞增生症(hemophagocytic lymphohistiocytosis,HLH)是一种以免疫功能紊乱伴多脏器、多系统受累的血液科危重症。继发于风湿免疫性疾病的HLH也称为巨噬细胞活化综合征(macrophage activation syndrome,MAS)。儿童MAS常被原发的风湿免疫性疾病掩盖而难以早期发现,病情危重,进展迅速,诊治难度大,而且MAS的治...
doi:10.1182/blood-2024-202475Background: Hemophagocytic Lymphohistiocytosis (HLH) is a rare life-threatening hyper-inflammatory disorder characterized by over-activation of the immune system. Medication induced HLH is a topic of growing scrutiny, particularly with increasing use of immunomodulatory therapies...
Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder with familial and acquired forms. The familial form is associated with mutations in the perfori... MB Jordan,D Hildeman,J Kappler,... - 《Blood》 被引量: 759发表: 2004年 Hemophagocytic lymphohistiocytosis (HLH) and related disorders He...
Bone marrow biopsy and peripheral blood analysis demonstrated aberrant increased myeloblasts along with hemophagocytosis. Ferritinemia with >36,000 ng/ml was present. The patient's neurologic examination was generally non focal, however, over the course of treatment he became lethargic. Subsequent ...
612 Words 3 Pages Open Document Try Paraphrasing tool INTRODUCTION: Hemophagocytic lymphohistiocytosis (HLH) is an incompletely understood condition resulting in uncontrolled and ineffective immune activation. HLH is classified as genetic HLH (primary) or acquired (secondary) and presents with a fulminant ...
Scientists at St. Jude Children's Research Hospital, UCSF Benioff Children's Hospitals and Baylor College of Medicine are investigating how to best treat hemophagocytic lymphohistiocytosis (HLH), a rare immune disorder. Their work, appearing as an advanc
Indian Society of Hematology and Blood Transfusion 2020Abstract A case series to illustrate diff i culties faced in diag-nosis, management and subsequent therapeutic approachpatients presenting with HLH secondary to lymphoma. A ret-rospectivereviewofpatientstreatedforHLHandlymphomainClinical Hematology depart...