We assessed the proficiency of HLA-B*5701 typing among numerous laboratories using a sequence specific primer (SSP)/ PCR assay.Methods: DNA was distributed to 6 laboratories for blinded typing of the HLA-B*5701 allele. Panel A (n=10 samples; n=6 laboratories) included 3 HLA-B*5701 ...
Cost-effectiveness analysis of HLA-B*5701 typing in the prevention of hypersensitivity to abacavir in HIV+ patients in Spain - ScienceDirect Introduction Approximately 4% to 8% of patients with HIV-1 treated with abacavir present a hypersensitivity reaction (HSR). Various studies have shown a di...