HLA-B*5701 typing: evaluation of an allele-specific polymerase chain reaction melting assay Hammond E, Mamotte C, Nolan D, Mallal S (2007) HLA-B*5701 typing, evaluation of an allele-specific polymerase chain reaction melting assay. Tissue ... E Hammond,C Mamotte,D Nolan,... - 《Tissue...
We assessed the proficiency of HLA-B*5701 typing among numerous laboratories using a sequence specific primer (SSP)/ PCR assay.Methods: DNA was distributed to 6 laboratories for blinded typing of the HLA-B*5701 allele. Panel A (n=10 samples; n=6 laboratories) included 3 HLA-B*5701 ...
Cost-effectiveness analysis of HLA-B*5701 typing in the prevention of hypersensitivity to abacavir in HIV+ patients in Spain - ScienceDirect Introduction Approximately 4% to 8% of patients with HIV-1 treated with abacavir present a hypersensitivity reaction (HSR). Various studies have shown a di...