在处方前,对患者HLA-B*5701基因分型可降低这种超敏反应。目前,FDA关于阿巴卡韦药物标签黑框警告中建议在使用阿巴卡韦前,对患者进行 HLA-B*5701基因检测,以减少超敏反应的发生风险。 Technical Data Allele 1 HLA-B*57:01 Allele 2 HLA-B*57:01 Buffer Tris-EDTA Sanger HLA-B*57:01 57:01 Sanger ...
2014年5月,在线发表在《Pharmacogenomics》的一项荟萃分析表明,HLA-B* 57:01检测预测阿巴卡韦高敏反应具有较高的诊断准确度,潜在HLA-B *57:01检测可显著降低阿巴卡韦诱导高敏反应的发生率。 目的:通过荟萃分析已发表的研究来确定HLA-B *57预测阿巴卡韦高敏反应的诊断准确率及量化预处理筛选的临床受益。 方法:研...
英文别名: iTAg Custom Tetramer/APC – HLA-B*57:01 (IP)中文名: 中文别名: CBNumber: CB815382810 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 iTAg Custom Tetramer/APC – HLA-B*57:01 (IP)化学性质 安全信息...
Tetramer/PE – HLA-B*57:01 HIV gag (147-155) (ISPRTLNAW) 中文名: 中文别名: CBNumber: CB115384547 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 Tetramer/PE – HLA-B*57:01 HIV gag (147-155) (ISPRTLNAW)化学性质 ...
procedures to screen the DrugBank database and identify potentially HLA-B*57:01 liable drugs. Then, we compared our workflow’s performance with another model recently developed by Metushi et al., which proposed seven in silico HLA-B*57:01 actives, but were later found to be experimentally ...
Herein, we present a structure-based analysis of the common HLA-B*57:01 variant known to be responsible for several HLA-linked adverse effects such as the abacavir hypersensitivity syndrome. First, we analyzed three X-ray crystal structures involving the HLA-B*57:01 protein variant, the anti-...
Real-Time PCR methods to typing HLA-B*57:01 Key words: HIV, antiretroviral therapy, immunogenetics Corresponding author Ombretta Turriziani Department of Molecular Medicine, Sapienza University, V.le dell’Università 31, 00185 Rome, Italy E-mail: ombretta.turriziani @uniroma1.it Page 1 of 22 ...
Recently, we investigated the binding mode of abacavir with the HLA-B*57:01 variant using molecular docking. Herein, we developed a new ensemble screening workflow involving three X-ray crystal derived docking procedures to screen the DrugBank database and identify potentially HLA-B*57:01 liable ...
中文名称: Custom Biotinylated Monomer – HLA-B*57:01(CP) (formerly code #MR02038) 中文同义词: 英文名称: Custom Biotinylated Monomer – HLA-B*57:01(CP) (formerly code #MR02038) 英文同义词: Custom Biotinylated Monomer – HLA-B*57:01(CP) (formerly code #MR02038) CAS号: 分子式: ...
Faculty Opinions recommendation of Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient. 来自 Semantic Scholar 喜欢 0 阅读量: 9 作者: P Goepfert DOI: 10.3410/f.732500556.793547581