1、HLA-DR4基因亚型在骨髓移植中的应用研究骨髓移植供、受体的HLA相合程度是决定移植成败的关键因素之一。HLA-DR4亚型在各人种中的频率均较高,且与骨髓移植后GVHD(graft-versus-host disease,移植物抗宿主病)的发生有关1-3。为探讨HLA-DR4基因亚型在骨髓移植中的意义,设计合成了HLA-DR4等位基因引物4,建立巢式PCR...
HLA-DR4 gene complexrheumatoid arthritisautoantibodiesThe HLA-DR4 gene complex plays a role in the pathogenesis of rheumatoid arthritis (RA). Auto-antibodies are a prominent serum feature of RA. In this study we explored the correlation of the HLA-DR4 gene complex with rheumatoid factor, anti-...
Synonyms MHC class II antigen DRB4, HLA DRB4, HLA DR4B, 230352F10 Calculated Molecular Weight 266 aa, 30 kDa Observed Molecular Weight 30 kDa GenBank Accession Number BC005312 Gene Symbol HLA-DRB4 Gene ID (NCBI) 3126 Conjugate Unconjugated Form Liquid Purification Method Protein A purification...
HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB). The alpha chain gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 enc...
HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB). The alpha chain gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 enc...
其他还包括HLA-DRB1*0101、HLA-DR4、MHC(HLA class)-IⅡ、低分子蛋白酶体(lowolecular weight proteasome.LMP)、抗原加工相关转运子(transporter associated with antigenrocessing,TAP)、主要组织相容性复合体I类相关基因A(major histocompatibility complexass I chain-related gene A,MICA)、肿瘤坏死因子-a(tumor ...
基因别名:CD74; DHLAG; DR-4; DR4; DRB1; DRB4; DRw10; HLA-DR1B; HLA-DR3B; HLA-DR4B; HLA-DRA; HLA-DRA1; HLA-DRB; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5; HLADG; Ia-GAMMA; II; MLRW; SS1 UniProt ID:(Human) P04233,(Human) P01903,(Human) Q4PRC3,(Human) Q7YQ62,...
HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB). The alpha chain gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 enc...
基因别名:CELIAC1; DPB1; DR-4; DR4; DRB1; DRB4; DRw10; HLA-DP; HLA-DP1B; HLA-DPB; HLA-DPB1; HLA-DQB; HLA-DQB1; HLA-DR1B; HLA-DR3B; HLA-DR4B; HLA-DRA; HLA-DRA1; HLA-DRB; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5; IDDM1; MLRW; SS1 ...
基因别名: CELIAC1; DPB1; DR-4; DR4; DRB1; DRB4; DRw10; HLA-DP; HLA-DP1B; HLA-DPB; HLA-DPB1; HLA-DQB; HLA-DQB1; HLA-DR1B; HLA-DR3B; HLA-DR4B; HLA-DRA; HLA-DRA1; HLA-DRB; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5; IDDM1; MLRW; SS1 UniProt ID: (Human) Q2...