Additionally, IFN-γ-educated CD33+HLA-DRlow MDSCs had less capacity to suppress T cell proliferation and activation. Neither NO production nor ARG-I activity influenced the immuno-suppressive potency of IFN-γ-educated MDSCs. Suppressive function of cytokine-induced MDSCs depended on PD-1/PD-...
见。(2)APL免疫表型特点为稳定表达CD9,CD13,CD33(CD33>CD13), CD64,CD38,cMPO;部分表达:CD34,CD117,CD16,CD10,CD2; 不表达:CD14,CD15,CD11b,CD4,HLA-DR,CD56,cCD79a,cCD3。 (3)CD9/CD11b/HLA-DR抗体组合在诊断APL时,具有较高的敏感性和 ...
To investigate the types of MDSCs or other myeloid cells expanded in the peripheral blood after G-CSF treatment in donors, the frequency and cell number of different MDSCs were analyzed. Total MDSCs (HLA-DR−/lowCD11b+CD33+), M-MDSCs (HLA-DR−/lowCD11b+CD33+CD14+CD15−), G-MD...