Conclusions Day 100 NKC/CD14+HLA-DRDIM ratio is a prognostic immune-biomarker in lymphoma patients post- APBHSCT.Luis F. PorrataStephen M. AnsellIvana N. MicallefPatrick B. JohnstonJose C. VillasboasJonas PaludoUrshila DuraniSvetomir N. Markovic...
The human monocytic CD14+HLA-DRDIM cells are associated with worse prognosis in NHL. Thus, we investigated whether the autograft A-NKC/A-CD14+HLA-DRDIM ratio predicts survival in NHL. In a total of 111 NHL patients, we analyzed apheresis collection samples for the content of A-NKC and A...
These decidual CD14+ or CD14− HLA-DR+ cells have an unusual phenotype that in some respects resembles dermal myelomonocytic cells. Nonetheless, the idea that a placental monomorphic molecule could be diverting all local immune responses from immunogenic to tolerogenic is attractive. If this is ...
To investigate the types of MDSCs or other myeloid cells expanded in the peripheral blood after G-CSF treatment in donors, the frequency and cell number of different MDSCs were analyzed. Total MDSCs (HLA-DR−/lowCD11b+CD33+), M-MDSCs (HLA-DR−/lowCD11b+CD33+CD14+CD15−), G-MD...
A humanized IgG4 anti–HLA-DR monoclonal antibody (IMMU-114), engineered to avoid side effects associated with complement activation, was examined for binding and cytotoxicity on leukemia, lymphoma, and multiple myeloma cell lines and chronic lymphocytic leukemia (CLL) patient specimens, followed by ...
不表达:CD14,CD15,CD11b,CD4,HLA-DR,CD56,cCD79a,cCD3。 (3)CD9/CD11b/HLA-DR抗体组合在诊断APL时,具有较高的敏感性和 特异性,可作为诊断APL和监测其MRD的抗体组合。 关键词:急性早幼粒白血病;流式细胞术;免疫表型;微小残留病变 山西医科大学硕士学位论文 ...
MDSCs can be further divided into two major subsets: the granulocytic MDSCs that display CD14−CD15+CD11b+CD33+ HLA-DRlow/− phenotype and monocytic MDSCs which have the phenotype of CD14+CD15−CD11b+CD33+ HLA-DR low/− (Damuzzo et al., 2015). The highly suppressive MDSCs ...
anti-Human HLA-DR (Mouse monoclonal) BioLegend Cat# 307663; Clone L243; RRID: AB_2800795 anti-Human IgG (Fc) (Rat monoclonal) BioLegend Cat# 410727; Clone M1310G05; RRID: AB_2801087 anti-Human TCR Vd2 (Mouse monoclonal) BioLegend Cat# 331435; Clone B6; RRID: AB_2800864 anti-Human...
65 - Infusion of Autograft Natural Killer Cells/CD14+hla-DRDIM Myeloid-Derived Suppressor Cells Ratio Predicts Survival in Non-Hodgkin Lymphoma Undergoing Autologous Peripheral Blood Hematopoietic Stem Cell Transplantation (APHSCT)The infusion of autograft absolute lymphocyte coun...
Infusion of autograft natural killer cell/CD14 + HLA-DR DIM cell ratio predicts survival in lymphoma post autologous stem cell transplantationThe infusion of autograft absolute lymphocyte count (A-ALC) and autograft natural killer cells (A-NKC) are prognostic factors for overall survival (OS) and...