Monocyte subset composition was determined by flow cytometry based on the expression of CD14, CD16, and HLA-DR. Monocyte subset composition and the expression of CD14 and HLA-DR were correlated with patient outcomes. The results were compared to 19 patients with coronary artery disease. Cardiac ...
DR/CD14表达率与CRP水平呈负相关(r=-0.704,P<0.01).对急重症疾病组15例患者进行动态观察显示:其中6例死亡患者HLA-DR/CD14表达率随病程进展呈持续下降状态,始终未能纠正,直至死亡;另外9例存活患者随病程好转,HLA-DR/CD14表达率逐渐上升至正常水平,临床症状也随之明显改善直至治愈.结论 外周血单核细胞表面HLA-DR/...
HLA-DR expression was decreased on each subtype of monocyte of NHL patients, among which the difference of intermediate monocyte (CD14++CD16+) (25.43 MFI vs. 33.52 MFI, P<0.01) and non-classical monocyte (CD14+CD16++) (11.40 MFI vs. 15.70 MFI, P< 0.01) were of statistical significance...
HLA-DR_CD14在外周血单核细胞中的表达及其临床意义 热度: 急性脑梗死患者单核细胞CD14+CD16+亚型的表达变化及临床意义 热度: 外科术后危重患者单核细胞HLA-DR表达的临床研究 热度: 相关推荐 ·临床研究· HLA-DR / CD14 在外周血单核细胞中的表达及其临床意义 李薇,谢闻悦,张卫云,张璇,张玉新,高贵阳 [...
Previous reports have described antigens that are recognized on human melanoma cells by autologous cytolytic T lymphocytes (CTL). The genes coding for a nu... B Gaugler,N Brouwenstijn,V Vantomme,... - 《Immunogenetics》 被引量: 286发表: 1996年 CD14, CD16 and HLA-DR reliably identifies hu...
HLA-DR是由36 kDa α链和27 kDa β链组成的异二聚体,由6号染色体短臂的MHC基因复合物编码。两条链可由许多不同的等位变异形态出现,存在高度的多态性。HLA-DR结构性表达在抗原递呈细胞上,主要表达于免疫系统的细胞[1]。HLA-DR在单核细胞上强表达,尤其是CD14+CD16+亚群[2];在巨噬细胞、粒细胞、浆样树突...
The number of CD14+CD16+ monocytes were significantly higher in the skin blister compared with peripheral circulation in both patients (P P = 0.005). In vivo extravasated monocytes had in comparison with peripheral monocytes a lower expression of CX3CR1, a higher expression of HLA-DR, CD86 ...
The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency HLA-DR(+) lineage(-) compartment, with virtually no CD123(+) or CD11c(+) dendritic cells (DCs) and very few CD14(+) or CD16(+) monocytes. The... Venetia,Bigley,Muzlifah,... - 《Journal of Experimental ...
Myeloid derived suppressor cells are present and predominantly localized in the ONB stroma To identify myeloid cells in the ONB TIME a mxIF panel of C11b, HLA-DR, CD14, CD15, CD68, and synaptophysin was used (Fig. 2A). Recent studies have shown that CD68+ is overexpressed in tumor asso...
目的:观察多器官功能障碍综合征(MODS)患者的免疫功能改变,寻求早期诊断手段.方法:采用免疫荧光技术连续监测28例ICU中重症感染、严重创伤患者的外周血单核细胞表面人类白细胞抗原DR位点(HLA-DR)抗原表达.结果:发生MODS患者HLA-DR抗原表达水平比未发生MODS者显著降低(P<0.05) ,而且其动态变化与预后有明显的相关性.结论...