HLA-A(major histocompatibility complex, class I, A) belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central...
1) HLA class I molecules HLA I类分子 1. Expressions ofHLA class I moleculesand MHC class I chain-related molecules A/B on NK-edited human nasopharyngeal carcinoma cell line CNE2 and their effects on cytotoxicity of NK cells; NK细胞免疫编辑后的人鼻咽癌细胞株CNE2HLA I类分子和MICA/MICB的表...
Tang Q, Zhang J, Qi B, Shen C, Xie W. Downregulation of HLA class I molecules in primary oral squamous cell carcinomas and cell lines. Arch Med Res. 2009;40(4):256-263.Tang Q,Zhang J,Qi Bet al.Downregulation of HLA class Imolecules in primary oral squamous cell carcinomas ...
All HLA class I molecules at the cell surface contain a tightly bound peptide, usually consisting of 8–10 amino acid residues. In healthy cells the peptides are derived from normal cellular components, whose routine turnover and degradation takes place in the cytoplasm. The peptides, called ...
Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes. Soluble HLA class I molecules (sHLAs) have been identified in the serum of patients with , allografts and and in serum of healthy individuals. The biologic... N Zavazava,Krnke, Martin - 《Nature Medicine》...
peptide loading by MHC class I molecules. Size:50ul Concentration:1mg/ml Applications:ELISA(1:5000-10000) IHC-P(1:100-500) IHC-F(1:100-500) IF(1:100-500) Cross Reactive Species:Human Mouse Rat Dog Pig Cow Horse Rabbit 仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
USE OF HLA CLASS 1 SOLUBLE MOLECULES TO INHIBIT ANGIOGENESISThe invention relates to the use of a HLA class 1 soluble molecule or a nucleic acid molecule comprising a polynucleotide sequence that codes for a HLA class 1 molecule for the preparation of pharmaceutical compositions that are intended ...
HLA class I molecules. However, early after CBT, the dendritic cells are mostly derived from recipients (not donors) due to the delayed achievement nature of donor chimerism compared to other peripheral blood or bone marrow cells21,22,23, and these recipient-derived dendritic cells are unbale ...
The loading and binding of peptides to class II molecules is controlled through an HLA DM-dependent process via the removal of the class II invariant chain peptide (CLIP) from the peptide-binding groove of class II proteins13. This action facilitates the loading of alternative peptides derived ...
hla-a belongs to the hla class i heavy chain paralogues. this class i molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). the heavy chain is anchored in the membrane. class i molecules play a central role in the immune system by presenting pept...