HLA class I polymorphism: structure and function and still questions. Hum. Immunol. 57:1.Kostyu, D.D., L.I. Hannick, J.L. Traweek, M. Ghanayem, D. Heilpern, and D.V. Dawson. 1997. HLA class I polymorphism: structure and function and still questions. Hum Immunol. 57:1-18....
8085Accesses 41Altmetric Metrics Abstract The class I histocompatibility antigen from human cell membranes has two structural motifs: the membrane-proximal end of the glycoprotein contains two domains with immunoglobulin-folds that are paired in a novel manner, and the region distal from the membrane ...
Class I major histocompatibility complex (MHC) molecules bind, and present to T cells, short peptides derived from intracellular processing of proteins. The peptide repertoire of a specific molecule is to a large extent determined by the molecular structure accommodating so-called main anchor positions...
Recombinant Human HLA class I histocompatibility antigen, alpha chain G (HLA-G) structure CAS No. Chemical Name: Recombinant Human HLA class I histocompatibility antigen, alpha chain G (HLA-G) Synonyms Recombinant Human HLA class I histocompatibility antigen, alpha chain G (HLA-G);Recombinant ...
Structure and Serology The HLA-A chain forms a binding cleft much like the MHC Class II molecules, the sides of the cleft are composed of alpha helices, the base is beta sheet and one end the relative closure limits the optimal length of peptide. ...
et al. Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur. J. Immunol. 52, 618–632 (2022). Article CAS PubMed PubMed Central Google Scholar Horowitz, A. et al. Class I HLA haplotypes form two ...
A set of conserved water positions making direct contacts with the alpha1 and alpha2 domains of the MHC class-I protein was identified by a cluster analysi... O Koji,SJ Wodak - 《Protein Eng》 被引量: 87发表: 2002年 Structure of HLA-A*1101 in complex with a hepatitis B peptide homolo...
*可分为下列功能区(1)肽结合区:结合抗原肽,多态性区域(1+1)(2)Ig样区:与CD4分子结合的部位(3)跨膜区和胞浆区HLAII类分子呈递外源性抗原肽给CD4+T细胞HLA-II类分子的结构ThestructureofanMHCclassIImolecules(resembleMHCclassImoleculesinstructure)人人文库> 全部分类> 教育资料 > 课设设计 ...
Golgins in the structure and dynamics of the Golgi apparatus conserved domain present in golgin-97, RanBP2α, Imh1 and p230/golgin-245Golgins are a family of coiled-coil proteins associated with the Golgi ... FA Barr,B Short - 《Curr.opin.cell Biol》 被引量: 454发表: 2003年 The ...
1b). Table 1 The HLA class I genotypes of the EBV-transformed B cells and transfectant hosts Full size table Fig. 1: Reactions of DQβ0603:DQα0103 specific sera to the DQβ0603:DQα0103 protein purified from five different B cell lines. DQβ0603:DQα0103 protein purified from five ...