We develop the HLA-B27 test kit using the PCR-SSP technique. Five hundred forty blood samples were tested for HLA-B27 by microlymphocytotoxicity test (LCT)... O Nathalang,S Tantimavanich,K Nillakupt,... - 《Tissue Antigens》 被引量: 22发表: 2010年 The Significance of HLA-B27 Testin...
We develop the HLA-B27 test kit using the PCR-SSP technique. Five hundred forty blood samples were tested for HLA-B27 by microlymphocytotoxicity test (LCT) and PCR-SSP. It was found that 127 (23.5%) and 134 (24.8%) of these samples were positive for HLA-B27 by LCT and PCR-SSP, ...
在SIJ MRI未发现炎症的患者中,可能存在结构性损害、硬化、糜烂和fJSW。然而,fJSW与SIJ MRI所见的炎症严重程度显著相关,有助于nr-axSpA的准确诊断,可作为普通人群中nr-axSpA的替代诊断试验,特别是对于未携带HLA-B27基因且无BME的亚洲...
Although HLA-B27 is positive more often in established disease—AS (80–90%), it is less commonly present in early phases of the disease in nr-axSpA patients (73–75%)[7,10]. Although the test has a good sensitivity, it has a low specificity as the prevalence of HLA-B27 inhealthy s...
Clinical application of the HLA-B27 test in rheumatic diseases. A current perspective. Testing for the histocompatibility antigen HLA-B27 has been suggested as a valuable diagnostic aid in patients with ankylosing spondylitis and associated s... M A,Khan - 《Archives of Internal Medicine》 被引量...
内容提示: ·论 著·流式细胞术检测 HLA-B27 两种试剂比较与结果分析*陈永强 1,郑 璐1,张 玥1 ,王杜平 1,程 星1 ,陈艳红 1 ,周忠海 2△ ,牛国平 1▲1.徐州市中心医院检验科,江苏徐州221009;2.徐州医科大学附属淮海医院实验科,江苏徐州221004 摘 要:目的 比较两种人类白细胞抗原B27(HLA-B27 )检测试剂...
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HLA-B27基因属于Ⅰ型MHC 基因，基本上表达在机体中所有含核的细胞上，尤其是淋巴细胞的表面有丰富的含量。早在二十多年前，人们就已发现HLA-B27抗原的表达与强直性脊椎炎有着高度相关性，超过90%的强直性脊椎炎患者其HLA-B27抗原表达为阳性，普通人群中仅5-10%的为阳性，而强直性脊椎炎由于其症状与许多疾病相似...
如降低其临界值, 提高流式细胞术检测HLA—B27抗原的阳性率,更符合临床诊断,有利于As患者的诊断和治疗。 【关键词】 HLA—B27;流式细胞术;强直性脊柱炎;临界值 ThecriticalvaluesettingdiscussionanalysisoffloweytometerdetectingHLA——B27fordiagnosingankylosing spondylitis LiuHong,JiaHongying(TheDepartmentofLaboratory...
HLA-B27 Ankylosing spondylitis, Juvenile rheumatoid arthritis, Reactive arthritis HLA-DQ2 and HLA-DQ8 Celiac disease HLA-DQB*06:02 Narcolepsy HLA-B*57:01 Abacavir hypersensitivity HLA-B*15:02 Carbamazepine hypersensitivity Is my blood type (ABO) related to my HLA genes and antigens? No. Altho...