HLA B27 and the genetics of ankylosing spondylitis. Ann Rheum Dis 1978;37:504 -9.Woodrow JC, Eastmond CJ. 1978. HLA B27 and the genetics of ankylosing spondylitis. Ann Rheum Dis 37:504-509.Woodrow JC, Eastmond C
强直性脊柱炎(Ankylosing spondylitis 简称AS) 又名类风湿脊柱炎。本病为脊柱各关节及关节周围组织的侵袭性炎症。一般先侵犯骶髂关节,其后由于病变发展逐渐累及腰椎、胸椎和颈椎,出现小关节间隙模糊、融合消失及椎体骨质疏松破坏、韧带骨化,终致脊柱强直或驼背固定。主要症状为发病部位疼痛,活动受限。是一种病因不明的常...
Severe uveitis in an HLA - B27 positive patient with ankylosing spondylitis [ J ]. Nat Cli Pract Rheumato1,2006,2 ( 7 ) :393 - 397.Monnet D, Moachon L, Dougados M, Brezin AP (2006) Severe uveitis in an HLA-B27-positive patient with ankylosing spondylitis. Nat Clin Pract Rheumatol ...
A HLA-B27 test can be used for many reasons. Let’s look at them. Confirm a suspected diagnosis of ankylosing spondylitis (AS), juvenile rheumatoid arthritis, or sometimes anterior uveitis. Rule out an autoimmune disorder. Evaluate signs and symptoms to understand your medical condition. ...
Conclusion HLA -B27 was highly associated with JAS . Key words:Ankylosing spondy litis ;Children ;HLA -B27 强直性脊柱炎(Ankylosing spondylitis)是一组好发 于 20 ～ 40 岁 , 主要症状为下腰痛 ,脊椎僵硬及运动范 围受限 , X 线显示有两侧骶髂关节炎(sacroilitis)为其 特征的疾炳 .该病在 80 ...
HLA-B27: The Facts HLA-B27 (an abbreviation for "Human Leukocyte Antigen B27") or HLA-B*27 (according to the most recent nomenclature) is one of the HLA class I surface molecules encoded in the B locus of the major histocompatibility complex (MHC) on the short arm of chromosome 6 (...
ankylosing spondylitispopulation studyA total of 119 unrealted B27+ AS patients and 165 B27+ healthy controls were included in this study. For all individuals HLA genotyping was performed using segregation data of parental haplotypes. The AS patients were clinically diagnosed according to the New ...
Distribution of HLA-B27 subtypes in patients with ankylosing spondylitis: The disease is associated with a common determinant of the various B27 molecules Ann Rheum Dis (1987) BSBreur-Vriesendorpet al. Identification of new B27 subtypes (B27C and B27D) prevalent in Oriental populations ...
【摘要】 目的 应用流式细胞术检测外周血白细胞 HLA - B27, 并结合临床诊断, 寻求诊断强直性脊柱炎( ankylosing spondylitis, AS) 的最适合临界值。方法 应用美国 Beeton Dickinson 公司流式细胞仪检测 95 例 AS 患者、226 例非 AS( 包括腰 腿背痛患者87 例, 其他 SPA 患者62 例, 类风湿性关节炎 43 例...
聚合酶链式反应SSP 法和酶联免疫吸附试验检测强直性脊柱炎患者HLA-B27的比较[J]. 工企医刊,2014,27(3):800-801.PENG Ping, ZHANG Hao, XIE Lihua. Comparison of polymerase chain reaction SSP method and enzymelinked immunosorbent assay for detecting HLA-B27 in patients with ankylosing spondylitis [J]...