HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc. Natl. Acad. Sci. U.S.A. 95:2979-2984(1998) 细胞图片: HL-1小鼠心肌细胞接受后处理 1) 收到细胞后,请检查是否漏液 ,如果漏液,请拍照片发给我们。 2) 请先在显微镜...
背景简介HL-1 Cardiac Muscle Cell Line is an immortalized mouse cardiomyocyte cell line able to continuously divide and spontaneously contract while maintaining a differentiated cardiac phenotype. HL-1 can be serially passaged without losing its differentiated cardiac myocyte phenotype, including morphological...
molecular pathways triggered by genetic defects in three of the main genes in ARVC and determine common and gene-specific molecular features.Cardiac HL-1 cell line was edited by CRISPR/Cas9 to generate Knock Outs (KO) of three of the most frequent causal genes in ...
Virus-Host Coevolution in a Persistently Coxsackievirus B3-Infected Cardiomyocyte Cell Line Decreasing host cell CAR expression was partially overcome by the CVB3-HL1 variant through CAR-independent entry into resistant cells. Moreover, CVB3-HL1 ... S Pinkert,K Klingel,V Lindig,... - 《Journal ...
The red line indicates the Bonferroni-corrected significance with a −log10p = 5.88 (α = 0.05). (b) The quantile-quantile plots showing the observed vs. expected log p-values are shown. (c) Schematic representing the haplotypes of 12 HY-suspected calves on chromosome 29. The exact ...
experiments,withprimaryadultorneonatalcardiomyocytes,theratventricularH9c2celllineor themouseatrialHL-1cells,providingintriguingexperimentalalternatives.Currently,itisnot clearhowH9c2andHL-1cellsmimictheresponsesofprimarycardiomyocytestohypoxiaand oxidativestress.Inthepresentstudy,weshowthatH9c2cellsaremoresimilartoprimary...
The Bottom Line When negotiating the division of your assets and debts, be realistic and don't expect the negotiations to go any better than your marriage. If you fought then, the chances are very good that you will fight now. This article has been edited and excerpted from the book "...
The homogeneous subclone of the HL1 atrial-derived cardiomyocyte cell line, HL1-6, spontaneously exhibits re-entry on a microscopic scale due to its slow conduction velocity and the presence of triggers, making it possible to examine re-entry at the cellular level.Houston, CharlesTzortzis, ...
In the present study, we first established an in vitro differentiation system to efficiently obtain mouse embryonic stem cell (mESC)-derived hair cell-like cells. Subsequently, a mESC line carrying a targeted disruption of Barhl1 was generated using CRISPR/Cas9 technology and subjected to the ...
Mouse melanoma cell line B16-FO, human malignant melanoma cell line G361, human osteogenic sarcoma cell line HOS and human breast adenocarcinoma cell line MCF7 were used. IC50 values, the drug concentrations lethal to 50% of the tumor cells, were estimated. One of the important mechanisms ...