Hypoxia induces Notch signal protein and mRNA expression in HK2 cells.Rui DuWenjuan SunLin XiaAli ZhaoYan YuLiJuan ZhaoHanmin WangChen HuangShiren Sun
Y784001中图分类号:R364.4:R692泸纠医学院研究生硕士学位论文缺氧/复氧条件下HK-2细胞黏附窒息新生儿中性粒细胞的作用及胞内信号转号机制的研究二Oo五年五月缺氧/复氧条件下HK一2细胞黏附窒息新生儿中性粒细胞的作用及胞内信号传导机制的研究摘要目的:建立缺氧/复氧(hypoxia/reoxygenation,H/R)诱导的人近曲肾小管...
Hypoxia induced miR-125a down-regulation in HCC cells and tumors Full size image Down-regulation of miR-125a promotes glycolysis in HCC cells under hypoxia Full size image HK2 is a miR-125a direct target involved in the Warburg effect ...
Objective To investigate the protective role of chloroquine preconditionning in hypoxia/reoxygenation injury in HK2 cells exposed to high glucose. Methods HK2 cells were randomly divided into three groups (n=6): high glucose group (HG), high glucose ...
First, we established MCF7 breast cancer cells stably expressing YAP short hairpin RNAs (shRNA) via lentiviral infection. Then, the stable cell lines were exposed to CM from cultured human THP-1 macrophages. The ability of cell migration was measured by transwell assay. The results showed that...
泸州医学院研究生硕士论文 HIF.1a在缺氧/复氧性HK.2细胞损伤中 作用及丹参干预研究 四川泸州医学院附属医院新生儿科 研究生郭琳导师董文斌教授 中文摘要 背景和目的:缺氧诱导因子一l(hypoxia inducible factor-1HIF一1)是 1 992年Semenza对经缺氧处理的Hep3B和HepG2细胞株的核提取物进 行电泳位移分析时首先被发现...
(ATF4) plays an important role in regulating glucose and lipid metabolichomeostasisin hepatocytes andadipocytes. However, its immunometabolic role in macrophage during sepsis remains largely unknown. In the present study, we found that the expression of ATF4 inperipheral blood mononuclear cells(PBMCs) ...
are still unknown. In this study, we used a UUOrat model to mimic renal f i brosis, which was examined by Masson and HE staining analysis. To explore theef f ects of ING4 on hypoxia-induced EMT, HK2 cells were treated with hypoxia to induce EMT and ING4 wasover-expressed in ...
Brusatol inhibits the growth of prostate cancer cells and reduces HIF-1α/VEGF expression and glycolysis under hypoxia Prostate cancer (PCa) has a high rate of morbidity and mortality, which urges us to find a unique and effective drug for treatment. Brusatol, a triterpenoi... M Wang,L Dai...
The mitochondrion, as the main site of aerobic respiration in cells, is one of the organelles that undergo damage immediately after ischemia and hypoxia [2]. In our previous study, we found significant mitochondrial damage in tissues and organs, such as vascular [3], intestines [4], and the...