Oxygen control in cell culture – Your cells may not be experiencing what you think!Cell cultureOxygenHypoxiaPhysioxiaPericellularHypoxia-inducible factorsSummarizes challenges with oxygen-related cell culture with emphasis on underoxygenation of cultures in physoxia or hypoxia.Highlights the risk of ...
3* and Xiaonan Cui1* Abstract Natural killer (NK) cells are unique from other immune cells in that they can rapidly kill multiple neighboring cells without the need for antigenic pre-sensitization once the cells display surface markers associated with ...
Consequently, in ours experiments hypoxia may take longer to develop and may not become a primary issue immediately. We are confident that the pH did not chance in the tubes at the end of the experimental time, as it should happen in case of full metabolic activity of the cells, for not...
Intercellular mitochondrial transfer (MT) is a newly discovered form of cell-to-cell signalling involving the active incorporation of healthy mitochondria into stressed/injured recipient cells, contributing to the restoration of bioenergetic profile and
Systemic chronic hypoxia is a feature of many diseases and may influence the communication between bone marrow (BM) and gut microbiota. Here we analyse patients with cyanotic congenital heart disease (CCHD) who are experiencing chronic hypoxia and characterize the association between bone marrow mesench...
Mesenchymal stem cells (MSCs) have emerged as a promising therapeutic strategy in regenerative medicine, demonstrating significant potential for clinical applications. Evidence suggests that MSCs not only exhibit multipotent differentiation potential but
Mesenchymal Stem Cells (MSCs) have been studied extensively for the treatment of several retinal diseases. The therapeutic potential of MSCs lies in its ab
The final evaluation of the four patients showed that 29% still had persistent motor problems.Instances of DREZ lesioning are comparatively rare. For particular individuals experiencing persistent BPA pain, this remains a plausible treatment alternative, albeit with a noteworthy complication rate. Further...
activated T cells are recognized and trapped in the liver due to adhesion molecules, remaining sequestered until they lose recognition molecules and express B220, at which point they undergo apoptosis [35]. As for why the liver can recognize and capture T cells, it is suggested that adhesion ...
Hypoxic cells are threatened by excessive ROS accumulation and decreased mitochondrial ATP produc- tion, which could be alleviated by Warburg effect11. Hypoxia tolerance is a process that cancer cells use to adapt to both energy depletion process and ROS attacks. Mitochondria, the powerhouse of ...