URF - 独特重组形式（Unique Recombinant Form），指的是在HIV病毒基因组中发现的独特重组事件。HIVdb - HIV药物抗性数据库（HIV Drug Resistance Database），是由斯坦福大学维护的一个用于预测HIV对抗逆转录病毒药物敏感性的数据库。WHO - 世界卫生组织（World Health Organization），是联合国下属的一个专门机构，...
URF - 独特重组形式(Unique Recombinant Form),指的是在HIV病毒基因组中发现的独特重组事件。 HIVdb - HIV药物抗性数据库(HIV Drug Resistance Database),是由斯坦福大学维护的一个用于预测HIV对抗逆转录病毒药物敏感性的数据库。 WHO - 世界卫生组织(World Health Organization),是联合国下属的一个专门机构,负责全...
Additionally, the studies utilized genotyping methods for evaluating HIVDR and employed the Stanford HIV Drug Resistance Database (http://hivdb.stanford.edu) for resistance assessment. Exclusion criteria comprised studies using data from gene banks or relying on information from medical records of ...
To estimate the fitness function under NFV selective pressure, clinical data was pooled from the Stanford HIV Drug Resistance Database (Kantor et al., 2001), from the University Hospitals, Leuven, Belgium, and from Hospital Egas Monis, Lisbon, Portugal, to create a treated population PT of 1...
1.2.3 耐药判定 将序列提交至斯坦福耐药数据库(Stanford HIV Drug Resistance Database, http://hivdb.Stanford.edu), 通过在线分析工具对耐药突变位点(drug resistance mutations, DRMs)鉴定和解释, 得到所有抗病毒治疗药物的耐药程度以及耐药突变位点情况。根据耐药评分将药物敏感性分为五个水平:敏感(0~9)、潜在耐...
The HIV resistance mutations were determined with the use of Stanford University HIV Drug Resistance Database. Results Subjects were majority males (88.61%, 1 346/1 519)and migrants(66.16%,1 005/1 519), and the proportion of HIV infections through Homosexual behavior were higher in infected ...
DRM analyses in PR-RT and IN regions were performed in the Stanford HIV Drug Resistance Database (https://hivdb.stanford.edu)59 using Stanford HIVdb Program Genotypic Resistance Interpretation Algorithm (https://hivdb.stanford.edu/hivdb/by-sequences)60. Inferred levels of resistance of HIV-1...
et al. (2010) Public database for HIV drug resistance in southern Africa. Nature, 464, 673.de Oliveira T, Shafer R, Seebregts C. Public database for HIV drug re- sistance in southern Africa. Nature. 2010;464:673.de Oliveira T, Shafer RW, Seebregts C (2010) Public database for ...
For a reference sequence, we used the subtype B consensus sequence, which was derived from an alignment of subtype B sequences maintained at the Los Alamos HIV Sequence Database (LANL), and available from the HIV Drug Resistance Database (HIVDB), Stanford University [16]. Phylogenetic ...
Mbisa JL, Fearnhill E, Dunn DT, Pillay D, Asboe D, Cane PA; UK HIV Drug Resistance Database. Evidence of self-sustaining drug resistant HIV-1 lineages among untreated patients in the United Kingdom. Clin Infect Dis. 2015;61(5):829-836.PubMedGoogle ScholarCrossref 21. Vernazza P, ...