Cho S, Park JS and Kang YK: Dual functions of histone-lysine N-methyltransferase Setdb1 protein at promyelocytic leukemia- nuclear body (PML-NB): Maintaining PML-NB structure and regulating the expression of its associated genes. J Biol Chem 286: 41115-41124, 2011....
Histone lysine methyltransferases (KMTs) are biomedically important epigenetic enzymes that catalyze the transfer of methyl group from-adenosylmethionine to lysine's nucleophilic 蔚-amino group in histone tails and core histones. Understanding the chemical basis of KMT catalysis is important for discerning...
The discovery of the first histone lysine methyltransferase was the result of bioinformatics, genetics, and biochemical approaches. The similarity of the SET domain to a plant methyltransferase is what prompted Jenuwein and colleagues to ask whether Su(var)3–9 was in fact a bona fide h...
Histone-Lysine N-Methyltransferase structure CAS No. 9055-08-7 Chemical Name: Histone-Lysine N-Methyltransferase Synonyms Anti-KIAA1506;Anti-Myeloid/lymphoid;Anti-H3 lysine-4 specific MLL3;Histone-Lysine N-Methyltransferase;Anti-Mixed-lineage leukemia protein 3 homolog;Anti-MLL3 (C-term) antibody prod...
A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-g transactivation. Nat Cell Biol 2007;9:1273e85.I Takada,M Mihara,M Suzawa.A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation.Nature Cell Biology. ...
英語化学名:Histone-lysine N-methyltransferase EZH2 (165-174) 别名: Histone-lysine N-methyltransferase EZH2 (165-174) CAS番号: 分子式: 分子量:0 EINECS: Mol File:Mol FileBrowse by Nationality Histone-lysine N-methyltransferase EZH2 (165-174) Suppliers Global suppliers Enquiry...
HMTs分为两类:赖氨酸甲基转移酶(Histone lysine methyltransferase,HKMTs)和精氨酸甲基转移酶(Protein arginine methyltrans ferases,PRMTs)(图6)(Liu et al., 2010)。 图6 赖氨酸或精氨酸残基上的组蛋白甲基化和去甲基化是一个复杂的、动态的表观遗传标记调控系统(Liu et al., 2010)。(a)一甲基化、二...
产品名称 MLL4 CT Histone lysine N methyltransferase MLL4 KIAA0304 Myeloid Lymphoid or Mixed lineage Leukemia Protein 4 WW Domain binding Protein 7 WBP 7 Trithorax Homolog 2 Lysine N methyltransferase 2D KMT2D 产品货号 MBS643382 产品价格 现货询价,电话:010-67529703 产品规格 产品品牌 Mybiosource...
Histone-lysine methyltransferase 专业医学词典 组蛋白赖氨酸甲基转移酶 与"Histone-lysine methyltransferase"相近的词条 ... histone-free double stranded DNA histone gene Histone kinase histone like protein、histone-like protein histone like protein(HLP) Histone-lysine methyltransferase histone methylase histone ...
Mammalian cells express dozens of H3K9 methyltransferases containing catalytic SET domains flanked by pre-SET and post-SET domains; these include su(var)3-9 homolog 1 (SUV39H1)/KMT1A, SUV39H2/KMT1B, SET domain bifurcated histone lysine methyltransferase 1 (SETDB1)/KMT1E, G9a/euchromatic his...