组蛋白甲基转移酶(Histone methyltransferases,HMTs)将S-腺苷甲硫氨酸(Sadenosylmethionine,AdoMet/SAM)上的甲基转移到组蛋白赖氨酸或精氨酸位点上以完成对组蛋白的甲基化修饰(图4)。HMTs分为两类:赖氨酸甲基转移酶(Histone lysine methyltransferase,HKMTs)和精氨酸甲基转移酶(Protein arginine methyltrans ferases,PRMT...
组蛋白甲基转移酶的分类根据底物和催化机制的不同,组蛋白甲基转移酶可以分为多种类型,包括:1. 赖氨酸甲基转移酶(Lysine Methyltransferase):这类酶能够将甲基基团转移到组蛋白赖氨酸残基上,主要参与调控基因表达。2. 精氨酸甲基转移酶(Arginine Methyltransferase):这类酶能够将甲基基团转移到组蛋白精氨酸残基上...
Histone lysine methyltransferase, suppressor of variegation 3-9 homolog 1, promotes hepatocellular carcinoma progression and is negatively regulated by microRNA-125b. Hepatology. 2013;57(2):637-647.Fan DN,Tsang FH,Tam AH,et al.Histone lysine methyltransferase,suppressor of variegation 3-9 homolog 1...
碧云天生物技术有限公司生产的A-366 (Histone Methyltransferase抑制剂),产品编号产品名称产品包装产品价格SD1092-5mgA-366(HistoneMethyltransferase抑制剂)5mg404.00元化学信息:化学名(3
该组蛋白-赖氨酸N-甲基转移酶(MLL 5)抗体(Histone-lysine N-methyltransferase (MLL5) antibody)产品的背景资料详情,请查看Covalab提供的产品说明书。 其他 Covalab位于法国,自1995年公司成立以来,在抗体开发和生产方面拥有卓越的经验。Covalab提供超过15000种产品,包括抗体和试剂盒。拥有多种针对流行和罕见靶标的一抗...
Histone lysine methyltransferases (KMTs) are biomedically important epigenetic enzymes that catalyze the transfer of methyl group from-adenosylmethionine to lysine's nucleophilic 蔚-amino group in histone tails and core histones. Understanding the chemical basis of KMT catalysis is important for discerning...
Histone-Lysine N-Methyltransferase CAS号: 9055-08-7 英文名: Histone-Lysine N-Methyltransferase 英文别名: Anti-KIAA1506;Anti-Myeloid/lymphoid;Anti-H3 lysine-4 specific MLL3;Histone-Lysine N-Methyltransferase;Anti-Mixed-lineage leukemia protein 3 homolog;Anti-MLL3 (C-term) antibody produced in rabbit...
Histone lysine methyltransferase (HKMT) are histone-modifying enzymes that catalyze the transfer of methyl groups to lysine and arginine residues of histon... M Sharma,C Dhiman,P Dangi,... - 《Systems & Synthetic Biology》 被引量: 4发表: 2014年 EHMT2 (euchromatic histone-lysine N-methyltrans...
Epigenetic mechanisms are fundamental to understanding the regulatory networks ofgene expression that govern stem cell maintenance and differentiation. Methylated histone H3 lysine 4 (H3K4) has emerged as a key epigenetic signal forgene transcription; it
Our results indicate that H3K9 methyltransferase BcDIM5 is required for H3K9 trimethylation to regulate the development and virulence ofB. cinerea. 展开 关键词: Botrytis cinerea histone H3 lysine 9 methyltransferase H3K9 trimethylation BcDIM5 virulence development ...