Elevated level of lysine 9- acetylated histone H3 at the MDR1 promoter in multidrug- resistant cells. Cancer Sci 2012; 103: 659-69.Toth,M.,Boros,etc.Elevated level of lysine 9-acetylated histone H3 at the MDR1 promoter in multidrug-resistant cells[J].2012,4(4)....
histone H3 lysine 9 acetylation Da Li 1,2* , Fang-Fang Bi 1 , Ji-Min Cao 3 , Chen Cao 4 , Bo Liu 5 and Qing Yang 1* Abstract Background: DNA methyltransferase 1 (DNMT1) plays a critical role in breast cancer progression. However, the ...
Histone methylation on lysine (K) residues can function to either activate or repress gene expression, depending on which lysine residues are methylated. In general, methylations at K4, K36, and K79 of histone H3 are involved in the activation of transcription, whereas methylations at K9 and ...
Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis. Size:50ul Concentration:1mg/ml Applications:WB(1:500-2000...
Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis. Size:50ul Concentration:1mg/ml Applications:ELISA(1:5000-...
Lysine methylation occurs primarily on histones H3 (Lys4, 9, 27, 36, 79) and H4 (Lys20) and has been implicated in both transcriptional activation and silencing (4). Methylation of these lysine residues coordinates the recruitment of chromatin modifying enzymes containing methyl-lysine bindin...
Histone H3 lysine 9 methylation [Me(Lys9)H3] is an epigenetic mark for heterochromatin-dependent gene silencing, mediated by direct binding to chromodomain-containing proteins such as Heterochromatin Protein 1. In the ciliate Tetrahymena, two chromodomain proteins, Pdd1p and Pdd3p, are involved in ...
Lysine methylation occurs primarily on histones H3 (Lys4, 9, 27, 36, 79) and H4 (Lys20) and has been implicated in both transcriptional activation and silencing (4). Methylation of these lysine residues coordinates the recruitment of chromatin modifying enzymes containing methyl-lysine binding...
. As expected, we found the highest enrichment was with the known sets of H3K9me3 regions, but also we found significant enrichment in enhancer regions marked by H3K27ac or H3K4me1 (histone H3 monomethylation on lysine 4) [46], and in H3K36me3 (histone H3 trimethylation on lysine 36...
We find that methylation of histone H3 on lysine 9 (H3K9me3), the modification bound by HP1 proteins, is a characteristic of the region coding for the variant exons of the CD44 gene. Likewise, this modification is enriched on DNA encoding HP1-sensitive variant exons of the PKN2 and TAF...