CHROMATINHigh-throughput chromosome conformation capture (Hi-C) technology has been applied to explore the chromatin interactions and shed light on the biological functions of three-dimensional genomic features. However, it remains challenging to guarantee the high quality of Hi-C ...
including blood oxygen saturation (SpO2) and 19 bio-indicators (e.g., erythropoietin, nitric oxide, and cardiac enzymes) (Supplementary Data7and8). We also included 37 whole-genome sequences30and high-throughput chromosome conformation capture (Hi-C) data from a...
including blood oxygen saturation (SpO2) and 19 bio-indicators (e.g., erythropoietin, nitric oxide, and cardiac enzymes) (Supplementary Data7and8). We also included 37 whole-genome sequences30and high-throughput chromosome conformation capture (Hi-C) data from a...
Eukaryotic genomes are rich in transposable elements (TEs), which shape genome evolution through expansions, eliminations and transpositions25. The TE contents of the 11 tomato genomes ranged from 64.3% to 74.5%, with long terminal repeat retrotransposons (LTR-RTs) representing the most abundant clas...
[4,5,6,7,8] as shown by a number of up-to-date studies. High-throughput chromatin conformation capture (Hi-C) [9] and Micro-C [10] technologies have been developed to quantitatively measure the number of interactions among all genomic loci pairs throughout the genome via high-throughput...
Here, we used the most advanced high-throughput chromosome conformation capture (Hi-C) technology to obtain high-coverage sequencing data of the C. quinquecirrha genome. We then anchored these data to the previously published contig-level assembly to improve the genome. Finally, a high-continuity...
We used a multifaceted sequencing approach for chromosome-scale assembly. For theCn. tallsample, 227 Gb of Nanopore sequencing reads (~114×), 124 Gb of Illumina reads for genome correction, and 213 Gb of high-throughput chromosome conformation capture (Hi-C) reads were generated and applied ...
We used a multifaceted sequencing approach for chromosome-scale assembly. For theCn. tallsample, 227 Gb of Nanopore sequencing reads (~114×), 124 Gb of Illumina reads for genome correction, and 213 Gb of high-throughput chromosome conformation capture (Hi-C) reads were generated and applied ...
tabacum were assembled using a third-generation PacBio sequencing platform combined with High-throughput Chromosome Conformation Capture (Hi-C)-facilitated scaffolding. Highly sensitive transcription-start-site-sequencing (TSS-seq) and transcription-termination-site-sequencing (TTS-seq) methods were developed...
The development of high-throughput sequencing has vigorously promoted research progress in plant genomics and genetics, especially single-molecule long-read sequencing and high-throughput chromatin conformation capture (Hi-C) technology, which have allowed complete plant genome sequencing and assembly at a...