High PSA levels may show body is fighting cancerOutlines the results of a study on the treatment of prostate cancer. Significance of the prostate specific antigen; Ability of the antigen to reduce metastases; Experiment on in vitro cells.Josefson...
Cancer immunotherapies such as bispecific T-cell engagers have seen limited adoption in prostate cancer (PC), possibly due to differing levels of cancer receptor expression and effector T-cell infiltration between patients and inherent defects in T-cell
Following treatment completion, patients were followed with mostly lab assessment until PSA progression, at which point, treatment was per investigator discretion.” Breast Cancer Overall survival (OS) results from the phase III TROPiCS-02 study of sacituzumab govitecan (SG) vs treatment of ...
which rely on metabolites as substrates or cofactors39,40,41,42. Here, we provide the evidence that HFD acts as a master effector of prostate cancer metabolism, creating an environment that favours histone hypomethylation and results in an enhanced MYC-driven...
Methods: Men with NCCN intermediate or high risk localized prostate cancer treated with RP at the Johns Hopkins Medical Institute (1992-2010) with at least 5 years of post-operative follow up were identified. Only men with initial undetectable PSA after surgery and who received no therapy prior...
studi 1310726-60-3 - Uses and synthesis methods Upatinib is a drug used to treat certain types of cancer, primarily renal cell carcinoma and metastatic pancreatic neuroendocrine tumors. The synthesis of upatinib is as follows: 1. First, 5-bromo-2-methylpyridine is reacted with ethyl ...
Objectives: To determine the incidence and magnitude of the rapid increase in the serum PSA (riPSA) level after high-intensity focused ultrasound (HIFU) therapy for prostate cancer, and its correlation with clinical factors. Methods: A total of 176 patients with localized prostate cancer underwent...
Cutaneous squamous cell carcinoma (cSCC) is the second most prevalent form of skin cancer, showing a rapid increasing incidence worldwide. Although most cSCC can be cured by surgery, a sizeable number of cases are diagnosed at advanced stages, with local invasion and distant metastatic lesions. ...
Objective High-dose-rate (HDR) brachytherapy boost represents a method to dose escalate in high-risk prostate cancer; the purpose of this analysis is to report long-term outcomes for a group of high-risk patients with Gleason 8 through 10 prostate cancer treated with HDR brachytherapy boost from...
Potential Paradigm Shift in Prostate Cancer Therapy “Enoblituzumab appears safe and seems to activate the immune system in a way that involves both T-cells and myeloid cells,” Shenderov says. “What this means is if these results can be replicated in a larger, randomized study, it opens ...