New York, NY - Researchers at Memorial Sloan-Kettering Cancer Center have found that change in PSA levels over time — known as PSA velocity — is a poor predictor of prostate cancer and may lead to many unnecessary biopsies. The new study of more than 5,000 men was published online ...
Prostate Cancer: Does PSA screening do more harm than good?doi:10.1038/nrurol.2009.63FarleySuzanne J.OAINature Reviews Urology
Five of these 21 patients (24%) were diagnosed with prostate cancer following biopsy, two of whom had a benign prostate examination. The study, therefore, demonstrates that normalisation of the PSA level prior to biopsy does not exclude the presence of prostate cancer even when the prostate ...
A number of potential mechanisms of action have been proposed to account for the cancer-preventive effects of tea and tea constituents (Figure 2). Among these are binding to and inhibition of specific high-affinity molecular targets, induction of oxidative stress, and enhancement of endogenous antio...
PSA and PSA velocity (PSAV, rate of PSA change over time) are biomarkers for diagnosis and prognosis of prostate cancer. Men who are at high risk for prostate cancer also have associated comorbidities for which they are taking NSAIDs and statins for long periods; therefore, it is important ...
However, test- ing total PSA (tPSA) levels to decide which patients should undergo a biopsy has been found to lead to high rates of false- negative and false-positive results. In men with false-negative results, cancer may be missed. Men with false-positive results may undergo unwarranted ...
nPSA is a strong independent predictor of freedom from PSA failure and PFS in patients with low and intermediate-risk localized prostate cancer treated with RT alone. Longer follow-up and larger patient numbers are required to confirm these observations. 展开 ...
MP86-14 DOES A SECOND CONFIRMATORY PSA ABOVE 4.0NG/ML LEAD TO THE DIAGNOSIS OF MORE CLINICALLY SIGNIFICANT PROSTATE CANCER?1. Establish independent SWOG operations at the Portland VA Medical Center. 2. Establish processes that enable site to maintain accrual goals for site through life of project...
cancer thyroid disease Parkinson's disease Alzheimer'sdisease Depression is a side effect of some medications in the elderly. Not taking medication for certain conditions may also cause depression. Other examples of risk factors for depression in the elderly include: ...
Conclusion: Rapid tumor washout of [177Lu]Lu-PSMA-I&T and low tumor dose despite high uptake of [68Ga]Ga-PSMA-11 are most likely caused by localization of PSMA-receptors on neovasculature rather than on the tumor cells, and unlike in prostate cancer cells, the PSMA-RL / PSMA-receptor ...