High PSALow volume diseaseRarely, patients with prostate cancer (PC) present with Prostate-Specific Antigen (PSA) scores >20ng/mL but otherwise very low-risk disease. Oncologists debate whether malignancies in these patients behave more comparably to low-risk or high-risk disease. Our objective ...
Prostate cancer is a common type of cancer that affects men, and it occurs in the prostate gland which is a part of the male reproductive system. High-risk prostate cancer refers to aggressive and advanced forms of the disease that are more likely to spread to other parts of the body. ...
targeted prostate biopsyObjectiveTo determine the association among prostate cancer gene 3 (PCA3) score, Prostate Imaging Reporting and Data System (PI-RADS) grade and Gleason score, in a cohort of patients with elevated prostate-specific antigen (PSA), undergoing magnetic resonance imaging/...
Prostate cancer (PCa) exhibits significant geoethnic disparities as reflected by distinct variations in the cancer genome and disease progression. Here, we perform a comprehensive proteogenomic characterization of localized high-risk PCa utilizing paired tumors and nearby tissues from 125 Chinese male pati...
2 The study’s eligible patients had clinically localized prostate cancer with clinical T1c to T3b disease that would be classified as intermediate or high risk by NCCN, with a PSA level less than 100 ng/mL. Men were randomized to receive 4 or 28 months of ADT. The minimum allowable ...
criteria as it would inflate the event rate. We also conducted univariate and multivariate analyses to associate the SFI-induced MYC signature with clinical outcome after adjusting for other clinicopathologic variables including pre-operative prostate-specific antigen (PSA) levels, seminal vesicle invasion...
Prostate-specific antigen (PSA) is the tumor marker most widely used in conjunction with digital rectal examination (DRE) for the early detection of prostate cancer (PCa). Due to its limitations, especially the high rate of false positive (FP) results, PSA screening of transplant candidates is...
High-risk Prostate Cancer Treated With Dose-escalated RT: An Analysis of Hormonal Therapy Use and Duration, and Prognostic Implications of PSA Nadir 鈮 to ... OBJECTIVES:: To determine prognostic factors to select high-risk men receiving dose-escalated radiation therapy (RT) who will have favorab...
2.Establishment and application of transplantable TRAMP-C2prostate cancermice model;TRAMP-C2可移植前列腺癌动物模型的建立及初步应用 3.The Differential and Diagnostic Value for Prostate Cancer of the Serum Free PSA and Total PSA and Their Ratio;血清游离PSA与总PSA及其比值对前列腺癌的鉴别诊断价值...
There was a relationship between stromal periostin expression and shortened PSA relapse free survival times in the training cohort (p < 0.05). Conclusions Our data indicate that periostin up-regulation is related to increased tumour aggressiveness in prostate cancer and might be a promising target ...