Downing, S., et al., Elevated levels of prostate-specific antigen (PSA) in prostate cancer cells expressing mutant p53 is associated with tumor metastasis. Mol Carcinog, 2003. 38(3): p. 130-40.Downing S,Bumak C,Nixdorf S,etc.Elevated levels of prostate-specific antigen (PSA) in ...
PSA is a substance whose elevated levels can indicate prostate cancer but can also be caused by prostate inflammation or enlargement or other conditions. Catalona, known as the father of the PSA screening, was the first to show in 1991 that a simple blood test measuring PSA levels could be ...
PSA levels without catheter ranged between 0.2 and 11.6 ng/ml (mean 4.47). All patients with age related elevated PSA underwent full investigation. In the 20 patients with normal baseline there was no statistical difference between PSA with and without catheter. In the group of 21 patients with...
Generally elevated in prostate cancer vs BPH, and is more sensitive than PSA at detecting extracapsular extension. 与PSA在prostatic皮膜50-100次比PSA分享80%氨基酸序列和被生产以集中。 在摄护腺癌比PSA通常被举起对BPH,和敏感在查出extracapsular引伸。 [translate] ...
In PolgD257A/D257A mice, the mean alternative allele frequency was significantly lower in mtDNA preps than in lrPCR enrichment. Polgwt/wt mice appeared to have higher average heteroplasmy levels, which were elevated in mtDNA preps compared to lrPCR amplification enrichment. Polgwt/wt mice have ...
PSA relapse was defined as re-elevated at PSA level ≥0.2 ng/mL after prostatectomy and was documented in 44 cases (19.1%). Berlin Cohort The investigated TMAs comprised 560 samples of radical prostatectomy specimens after surgery in the Department of Urology (Charité University Hospital Berlin) ...
For instance elevated PSA predicts prostate cancer only 20% of the time. Additional biomarker的证明为多数癌症是非常困难的。 当前为多数癌症,没有biomarker可利用。 为那些biomarkers被辨认了的地方, biomarkers有非常恶劣的预计值。 例如高的PSA预言时间的摄护腺癌仅20%。 另外,当肿瘤进步,一特定biomarker变得...
Recent studies show that the PSA test is not an accurate indicator of prostate cancer. There are cases in which some men who don’t have prostate cancer are diagnosed with it. As a result, they undergo unnecessary and dangerous invasive treatments with many long-term side effects. Post-void...
(PSA). A protein produced by prostate cells. Its levels in the blood are elevated in prostate cancer. PSA is therefore used as a prostate cancer screening tool. Gleason score A commonly used system to stage prostate cancers, based on their pathological features. Pap smears The Papanicolaou test...
Objective To determine if fPSA / tPSA 0. 16 an indication for prostate biopsy in patients with tPSA 4ng / ml. Methods The prostate cancer( PCa) patients with t PSA 4ng / ml entered our center during2008 to 2014 were retrospectively analyzed. Four subgroups were divided. A group: f /...