Downing, S., et al., Elevated levels of prostate-specific antigen (PSA) in prostate cancer cells expressing mutant p53 is associated with tumor metastasis. Mol Carcinog, 2003. 38(3): p. 130-40.Downing S,Bumak C,Nixdorf S,etc.Elevated levels of prostate-specific antigen (PSA) in ...
An abnormally high serum PSA is still the most frequent trigger for men to enter a suspected prostate cancer diagnostic pathway. Large prostates, especially the ones with a volume over 100 cc, are commonly associated with elevated PSA levels. In men with benign prostatic hyperplasia (BPH), PSA...
AbstractProstate-specific antigen (PSA) is well known as a specific tumor marker for prostate cancer, but carcinoembryonic antigen (CEA)- and carbohydrate antigen 19-9 (CA19-9)-elevating adenocarcinomas originating in the prostate gland are rare. We report a case of metastatic adenocarcinoma of th...
OBJECTIVES: We tested the hypothesis that prostate-specific antigen (PSA) levels would be higher among prostate cancer deaths as compared with controls over time in the 25-year follow-up of the Multiple Risk Factor Intervention Trial of participants ages 35-57 at entry. METHODS: The initial stor...
Objective: To evaluate early postoperative results of patients with elevated prostate-specific antigen (PSA) levels who underwent surgery due to benign prostatic hyperplasia (BPH). Patients and Methods: 64 patients who had lower urinary tract symptoms (LUTS), normal digital rectal examinations (DRE),...
For instance elevated PSA predicts prostate cancer only 20% of the time. Additional biomarker的证明为多数癌症是非常困难的。 当前为多数癌症,没有biomarker可利用。 为那些biomarkers被辨认了的地方, biomarkers有非常恶劣的预计值。 例如高的PSA预言时间的摄护腺癌仅20%。 另外,当肿瘤进步,一特定biomarker变得...
PURPOSE: Patients with persistent elevated PSA and repeated negative prostate biopsy, that means having the prostate biopsied at multiple times, were investigated with 18F-choline PET/CT to delineate prostate cancer and guide renewed prostate biopsy. METHODS: Twenty patients with elevated PSA and negati...
Raised blood pressure predicts prostate cancer and elevated PSA in a large unselected population of men participating in the protect studyRaised blood pressure predicts prostate cancer and elevated PSA in a large unselected population of men participating in the protect studyhormone therapymagnetic...
Elevated levels of apoptosis regulator proteins p53 and bcl-2 are independent prognostic biomarkers in surgically treated clinically localized prostate cancer. J Urol 1996;156:1511- 6.Bauer JJ, Sesterhenn IA, Mostofi FK, McLeod DG, Srivas- tava S, Moul JW. (1996). Elevated levels of ...
手术成功后,PSA应该降低到检测不到的水平(198,199)。坚持PSA升高残留病的证据。但是,反过来不一贯主张,即不到PSA术后表示手术治愈。可能经过相当长的时间,通过检测PSA残留病前变得明显。最常用的是,残留病手术3年之内将宣布。高达20%至30%的男人谁接受RAD-ICAL前列腺癌目前在手术后第10年残留病。