Effect of high dose statin preloading on TIMI flow in patients presenting with ST-Elevation Myocardial Infarction undergoing Primary Percutaneous Coronary InterventionHigh intensity statinsSTEMIPrimary PCIAIM AND OBJECTIVES. The aim of this study was to assess the impact of high in...
Therefore, statin initiation and intensity of statin dose are left to the discretion of the provider. In women of reproductive age, concerns about the potential teratogenicity of statin therapy may present a barrier to initiation of treatment. Statins continue to be considered teratogenic and are ...
Among statin users, most were commenced on treat- ment within 90 days after stroke (84.3%) with a medium- intensity dose (73.8%). Those who did not change initial intensity through 2 years accounted for 86.4%. These statin use patterns were similar between patients with specified ischemic ...
Rockberg J, Jorgensen L, Taylor B, Sobocki P and Johansson G: Risk of mortality and recurrent cardiovascular events in patients with acute coronary syndromes on high intensity statin treat- ment. Prev Med Rep 6: 203‑209, 2017....
Importance In phase 2 studies, evolocumab, a fully human monoclonal antibody to PCSK9, reduced LDL-C levels in patients receiving statin therapy. Objective To evaluate the efficacy and tolerability of evolocumab when used in combination with a moderate- vs high-intensity statin. Design, Setting, ...
Accordingly, we designed the ASTEROID trial (A Study to Evaluate the Effect of Rosuvastatin on Intravascular Ultrasound-Derived Coronary Atheroma Burden) to examine the effects of high-intensity statin therapy on IVUS-derived measures of coronary disease progression. Rosuvastatin is the most recently ...
However, multiple factors will need to be considered, such as the amount of prior IL-2 received, the intensity of side effects experienced, and other treatment options. In addition, it should be noted that retreatment with IL-2 alone in this setting may be less effective [57]. Establishing...
Alirocumab Added to High-Intensity Statin Therapy and Coronary Atherosclerosis in Patients With Acute Myocardial Infarction—Reply JAMA Comment & Response September 6, 2022 Alirocumab Added to High-Intensity Statin Therapy and Coronary Atherosclerosis in Patients With Acute Myocardial Infarction JAMA Comment ...
QuestionIs an alternative low-density lipoprotein (LDL) cholesterol-lowering strategy associated with differences in long-term efficacy and safety in patients with atherosclerotic cardiovascular disease (ASCVD) compared with a high-intensity statin strategy?
Methods of using a high-dose statin for treatment of AMD in a patient can be used to regress drusen and/or drusenoid pigment epithelial detachments (PEDs), to prevent atrophy of the