(1) Background: Moderate-intensity statin therapy, when compared to high-intensity statin therapy in Asian populations, has shown no significant difference in cardiovascular prognosis in small studies. The aim of this study was to compare the prognosis of patients based on statin ...
Main Outcomes and Measures High adherence to high-intensity statins at 6 months and 2 years after discharge was defined by a proportion of days covered of at least 80%, down-titration was defined by switching to a low/moderate-intensity statin with a proportion of days covered of at least ...
1 This estimate was based largely on trials of moderate-intensity statin therapy. However, high-intensity atorvastatin (80 mg) has been shown to reduce CVD events more than moderate-intensity statins (atorvastatin [10 mg], pravastatin [40 mg], or simvastatin [20-40 mg]) in individuals with ...
In recent decades, the evidence from large randomized clinical trials with statins shows that lowering cholesterol reduces cardiovascular mortality, the incidence of acute myocardial infarction and cerebrovascular accident. The first clinical trials compared moderate-intensity statins versus placebo. Subsequently...
Effect of Very High-Intensity Statin Therapy on Regression of Coronary Atherosclerosis: The ASTEROID Trial Prior intravascular ultrasound (IVUS) trials have demonstrated slowing or halting of atherosclerosis progression with statin therapy but have not shown con... M Clearfield - 《Current Atherosclerosis...
However, of those on high-intensity statin, 25% remained on insufficient statin dosage. Conclusion Switch to high-intensity statins and use of ezetimibe and PCSK9i was low in chronic ASCVD patients. Even though statin intake was high in high-risk patients, target levels were still not reached...
2024 Select Your Interests Others Also Liked Non-statin lipid-lowering therapy in coronary atherosclerosis regression: a meta-analysis and meta-regression L.M Lobo, European Heart Journal, 2020 Statin induced myalgia on high intensity statin in patients with Acute Coronary Syndrome D Kumar, European ...
CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin Mohammed G. Maslub, Nur Aizati Athirah Daud, Mahasen A. Radwan, Abubakar Sha’aban & Arafa G. Ibrahim European Journal of Medical Research volume 29,...
High-intensity statins reduce CVD risk following AMI among patients with and without DM. We determined the proportion of Medicare beneficiaries 66 to 75years of age taking a low/moderate-intensity statin with (n=6718) and without (n=6414) DM who titrated to a high-intensity statin dosage (i...
1,4,24 The 2018 AHA/ACC Cholesterol Guideline recommends an LDL-C threshold of 70 mg/dL or greater in patients with atherosclerotic cardiovascular disease to consider adding nonstatin therapy to high-intensity statin therapy, and the European Society of Cardiology recommends an LDL-C goal of ...