Introduction: High-grade serous ovarian cancer (HGSOC) is the most common histological subtype of ovarian cancer, and is associated with high mortality rates. Methods: In this study, we analyzed specific cell subpopulations and compared different gene functions between healthy ovar...
海外直订Tumor Microenvironment High Grade Serous Ovarian Cancer 高级别级别浆液卵巢癌的肿瘤环境科普读物 683元 (包邮,需用券)价格:783元满600减20每300减40淘金币可抵3%满1600减50满300减5满1000减30海外直订The Tumor Microenvironment of High Grade Serous Ovarian Cancer 高级别浆液性卵巢癌的肿瘤微环境20...
High-grade serous ovarian carcinoma (HGSOC) is the most frequent type of ovarian cancer and has a poor outcome. It has been proposed that fallopian tube cancers may be precursors of HGSOC but evolutionary evidence for this hypothesis has been limited. Here, we perform whole-exome sequence and...
High-grade serous tubo-ovarian cancer (HGSTOC) is characterised by extensive inter- and intratumour heterogeneity, resulting in persistent therapeutic resistance and poor disease outcome. Molecular subtype classification based on bulk RNA sequencing facilitates a more accurate characterisation of this heterog...
A clinically applicable molecular classification for high- grade serous ovarian cancer based on hormone receptor expression. Sci Rep. 2016; 6:25408.Feng Z, Wen H, Bi R, Ju X, Chen X, Yang W, Wu X. A clinically applicable molecular classification for high- grade serous ovarian cancer based...
High-grade serous ovarian cancer (HGSC) recurrent tumor tissues (n=12) were obtained from the University Health Network Tissue BioBank under a Research Ethics Board approved protocol (11-0022-T). Each tumor originated from a different (unique) HGSC case and was verified by a gynecologic patholog...
High grade serous ovarian carcinoma (HGSOC) accounts for ~ 70% of ovarian cancer cases. Non-invasive, highly specific blood-based tests for pre-symptomatic screening in women are crucial to reducing the mortality associated with this disease. Since
In 2020, ovarian cancer was the fourth most lethal cancer for women in countries with a very high health development index [62]. Primary treatment for ovarian cancer consists of a combination of debulking surgery and chemotherapy. High grade serous ovarian cancer (HGSOC) is the most prominent ...
Origin and molecular pathogenesis of ovarian high-grade serous carcinoma. A new paradigm for the pathogenesis of ovarian cancer has recently been proposed which helps to explain persistent problems in describing the development a... Kurman,J R. - 《Annals of Oncology》 被引量: 166发表: 2013年 ...
Despite recent advances in the management of BRCA1 mutated high-grade serous ovarian cancer (HGSC), the physiology of these tumors remains poorly understood. Here we provide a comprehensive molecular understanding of the signaling processes that drive HGSC pathogenesis with the addition of valuable ubiq...