High-dose chemotherapy with bone marrow rescue for high-grade gliomas in adults. Cancer Invest 2001; 19(1):41-8.Brandes AA, Palmisano V, Pasetto LM, et al. High-dose chemotherapy with bone marrow rescue for high-grade gliomas in adults. Cancer Invest 2001; 19(1):41-8....
摘要: Malignant gliomas are the most common primary brain tumor in adults, with an incidence of five cases per 100,000 persons per year. Grade IV glioblastoma is the most aggressive form and prognosis remai关键词: Glioblastoma Malignant glioma Immunotherapy Tumor vaccine Bispecific antibody Checkpoint...
High-grade gliomas are the most common primary tumors in the central nervous system (CNS) in adults. Despite efforts to improve treatment by combination therapies (neurosurgery, radio- and chemotherapy), high-grade glioma patients still have a grim prognosis, indicating an urgent need for new ther...
Summary Patients with high-grade glioma (HGG) can be classified as having a favourable prognosis (younger or with good performance status) or a poor prognosis (older or with poor performance status) with median survival of 12–24 months and 6–9 months, respectively. The standard management for...
high grade gliomaimagingThe treatment options and prognosis in gliomas could be determined by anatomic topographic location, beside different subtypes of glioma. The aim of this study is to find if any correlation between anatomical location of a glioma and the different subtypes of high grade ...
High-grade gliomas (HGGs) constitute approximately 10 % of all childhood brain tumors and include AA (anaplastic astrocytoma), anaplastic oligodendroglioma (AO), and glioblastoma (GBM). Clinical symptomatology varies greatly with age and can be nonspecific, especially in younger children. Conventional ...
High-grade gliomas (HGGs) are central nervous system (CNS) tumors that occur in both children and adults, although bear distinct molecular features and neuroanatomy in younger compared with older patients [1,2,3,4]. While these types of cancers are relatively rare, patient prognosis is quite ...
gliomas can also drastically impair or disrupt vital functions. In children, these tumors can develop in midline structures like the brainstem (e.g., diffuse intrinsic pontine gliomas or DIPG), and due to their anatomic location, they are often unresectable and associated with significant morbidity...
High-grade gliomas (HGGs) are vascular tumors that represent attractive targets for antiangiogenic therapies. In this Review, we present the rationale and clinical trial evidence for targeting angiogenesis in HGGs, focusing predominantly on agents that target vascular endothelial growth factor (VEGF) ...
Gliomas are the most common malignant brain tumors in adults. High-grade gliomas (HGGs), which include grade III anaplastic astrocytomas and grade IV glioblastomas (GBMs), the deadliest form of brain tumor, are notoriously heterogeneous at the cellular level [1,2,3,4,5]. While it is well...