Objectives: To investigate the clinical and prognostic significance of absolute basophil count (ABC) in patients with primary myelofibrosis (PMF). Methods: We retrospectively investigated 58 patients with PMF treated in our institution in the period from 2006 to 2017. ABC was obtained in addition to...
Interestingly, after 12 weeks (W1) of nivolumab treatment, percentages of CD4+CD26high T cells were significantly higher in comparison with the frequencies measured at W0 (p < 0.0001), aligning the cell counts with the ranges seen in the blood of healthy subjects. Conclusions Our study ...
Seven pts (5 male, median age 58 yrs) with MRCC were tx'd with HDIL-2 and DD in different schedules to determine safety and effect on immune response as manifested by changes in T, lymphocyte, and peak eosinophil counts. Pts were tx'd with IL-2 600,000 IU/kg Q8H on days (d) 1...
(F) The absolute eosinophil count at diagnosis is shown in PTCL, NOS patients stratified by GATA-3 expression. (G) Unsupervised clustering of PTCL, NOS (n = 31), CTCL (n = 11), and reactive lymph nodes (RLNs; n = 7) on a panel of Th1-associated (T-bet, IFN-γ, CXCR3) and...
Relationship between total serum immunoglobulin E levels, fractional exhaled breath nitric oxide levels and absolute blood eosinophil counts in atopic and non-atopic asthma: a controlled comparative study J Breath Res, 12 (2018), Article 026009, 10.1088/1752-7163/aa95da View in ScopusGoogle Scholar...
Derp1IgEopticaldensityinELISAonthesubgroupsthat becamenegativeforhelminthinfectionregardlessoftheirpreviousinfectionconditioninpopulation1. Facingthat,weevaluatedtheanti-Derp1IgEreactivityindex,andtheratio(after/beforetreatment)was significantlyhigherinpatientsco-infectedbeforetreatment.Ontheotherhand,noassociation...
A competitive ELISA was adapted and optimized for quantification of the RBD antigen produced in HEK293SF cells in suspension, following principles and guidelines for the quantification of SARS-CoV-2 antigens [18]. The conformation-dependent CR3022 monoclonal antibody (Absolute Antibody, Boston, MA,...
single-centre observational cohort study including patients with severe refractory T2-high asthma in treatment with mepolizumab. After 12 months of treatment with mepolizumab, significant improvements (p< 0.0001) in asthma control and lung function were recorded. Rates of clinically significant annual asth...