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Dogs in the APOQUEL group had a slight decrease in mean white blood cell counts (neutrophil, eosinophil, and monocyte counts) that remained within the normal reference range. Mean lymphocyte count for dogs in the APOQUEL group increased at Day 7, but returned to pretreatment levels by study ...
They are likely caused by low grade inflammation driven by oxygen stress as indicated by the increase of pro-inflammatory cytokines such as IL-6, IL-1 and TNF-α, genes encoded by activation of nuclear factor kappa-B (NF-κB) [7]. Curcumin shows strong anti-oxidation and anti-inflammatory...