The present invention relates to an antibody that binds IL-5R for use in reducing the numbers of basophils in a human subject. In a specific embodiment, the antibody is administered parenterally. In another specific embodiment, the post-administration reduction in absolute basophil count is of at...
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cell. A reduction in eosinophils may lead to a reduction in inflammation (swelling) in the esophagus, and improve symptoms. Histological disease remission (based on eosinophil count) was achieved in 60% and 59% of patients in the active group compared to 5% and 6% of patients receiving ...
Also, curcumin may inhibit PI3K/Akt/NF-κB signaling pathway, reduce the inflammatory response, and thus provide a protective effect against CVB3-induced myocarditis [77]. Curcumin was found to stimulate the apoptotic cell death of H9c2 cells by upregulating ROS generation and triggering activation ...