(d) Immunohistochemistry using an antibody against Sox9 for paraffin-embedded polyps from small intestine (SI) and large intestine (LI). Genotypes of mice are as indicated. Scale bar ¼ 50 mm. inhibitors, disheveled, providing an additional Wnt- related mechanism by which Sirt1 may promote ...
Inhibition of TGF-β1 with a specific antibody in HTSF resulted in a statistically significant decrease in the expression of p21cip1 and p15ink4b compared to HTSF–TGF-β1 (2- and 14-fold, respectively). These results indicated that TGF-β1 controls the expression of cell-cycle proteins; ...