Unfractionated heparin (UFH) dosing may need to be adjusted when used in obese patients. The prevalence of pediatric obesity is increasing and, to our knowledge, no data exist to determine the effect of obesity on UFH therapy in children.To determine whether obese pediatric patients who receive ...
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“other”], body mass index [BMI, calculated as weight in kilograms divided by height in meters squared], illness severity [moderate vs severe], baseline respiratory support requirements, baseline D-dimer, prerandomization thromboprophylaxis dosing, and time since hospital admission), using ...
The Impact of Obesity on the Effect of Intravenous Heparin Using A Standardized Dosing Nomogram.: 539Barletta, Jeffrey FDeYoung, Jaculin LMcAllen, KarenBaker, RandalPendleton, KevinCritical Care Medicine
Although this procedure has been proven effective in reducing the morbidity and mortality of obesity and associated health care costs, it is elective and risk must be minimized. No dosing guidelines exist for pharmacologic prophylaxis in obese patients who are already at increased risk for these ...
Running head: THE EFFECT OF HEPARIN THERAPY IN OBESE PATIENTS WITH VENOUS THROMBOEMBOLISM The Effect of Heparin Therapy in Obese Patients with Venous Throm... Thrombembolism,C Snyder 被引量: 0发表: 0年 Dosing of Unfractionated Heparin in Obese Patients with Venous Thromboembolism BACKGROUND ...
The aim of this study was to assess patterns and accuracy of weight estimation and implications for drug dosing. Methods: The study comprised three parts: (1) inpatient weight documentation was reviewed over a 4 week period (January 2008); (2) a questionnaire was distributed to healthcare ...
Purpose. The performance of a weight-based dosing protocol for unfractionated heparin (UFH) infusions using antifactor Xa monitoring was evaluated. Methods. The first 50 patients to receive a UFH infusion per the new protocol for over 24 hours, regardless of indication, were included in the anal...
UFH dosingBackground The effect of obesity on the pharmacokinetics and pharmacodynamics of unfractionated heparin is not clearly understood, therefore to reduce the risk of bleeding, maximal dose (capped) nomograms are often used. This can lead to inadequate anticoagulation and increased mortality and ...
The impact of severe obesity on weight-based heparin dosing is not well studied. We performed a retrospective analysis of 424 patients undergoing percutaneous coronary intervention who received heparin for anticoagulation. We collected detailed data on cumulative heparin administration and measured ACT ...