Sickle Cell Trait and Hemoglobin C Trait说明书
Conclusion: Black children with sickle cell trait or hemoglobin C trait have an increased risk of invasive pneumococcal disease. 展开 关键词: Humans Streptococcus pneumoniae Pneumococcal Infections Sickle Cell Trait Hemoglobin C Population Surveillance Child, Preschool Infant, Newborn Infant Risk Factors ...
N. M. Nseka心血管病(英文)Lepira FB, Mukendi TK, Mbutiwi FIN, Makulo JR, Sumaili EK, Kayembe PK, et al. Sickle cell trait, hemoglobin levels and anemia among black patients with predialysis chronic kidney disease: a post hoc analysis. World J Cardiovasc Dis. 2016;6:258....
Materials and Methods: Three groups were studied and consisted in 31 controls (group AA), 26 sickle cell trait (group AS) and 29 SCD patients (group SS) at steady state. Hemoglobin phenotype was assessed by combination of cation-exchange high performance chromatography (beta-thal short program ...
Patients with sickle cell trait may experience mild if any, symptoms at all. In sickle cell disease, symptoms are more significant, especially in episodes of acute crisis. These symptoms can include: Generalized body aches and pain Chest pain Bone pain Shortness of breath Ulceration of the ...
Sickle cell anemia can usually be diagnosed simply by looking at a blood smear (Figure 12.14). In those suspected of being heterozygous carriers (usually called sickle trait), deoxygenating blood will often lead to the ability to see some distorted RBCs. In recent years, electrophoretic and ...
Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions
trait the haemoglobin is usually normal or only marginally reduced. Examination of a blood film stained by a Giemsa method may be helpful in confirming the diagnosis. However, definitive diagnosis often rests on electrophoretic or chromatographic analysis of haemoglobin in red cell haemolysates. ...
In cases of hereditary persistence of fetal hemoglobin, genetic determinants that affect transcription include point mutations or large deletions within the β-globin locus5 as well as quantitative trait loci on chromosomes 2p15,6 6q23,7 and 8q11.8 It is assumed that the capacity to induce HbF...
(fetal hemoglobin) and HbA2, both of which can be elevated in thalassemia, a relatively common condition characterized by an imbalance of hemoglobin alpha and beta subunits. Beta thalassemias can also occur in the presence of HbE and HbS, and the combined sickle/beta thalassemia trait occurs ...