The sickle cell trait (hemoglobin S), for example, is found chiefly in those regions of the tropical world where malaria is endemic. Hemoglobin S in its heterozygous form (inherited from one parent only) confers some immunity to those people who carry it, although it brings a deadly disease...
Hemoglobin S:The most common type of abnormalhemoglobinand the basis of sickle celltraitand sickle cellanemia. Hemoglobin Sdiffers from normal adult hemoglobin (called hemoglobin A) only by a singleamino acidsubstitution (a valine replacing aglutaminein the 6th position of the beta chain of globin...
Sickle Cell Trait and Hemoglobin C Trait说明书
sickle-shaped, which can cause death. A person in whom both beta-globin genes are abnormal (they produce hemoglobin S) has sickle cell disease, which can cause serious problems. Both parents must have either the sickle cell trait or the disease itself for a child to have sickle cell disease...
hemoglobin s (hbs) is one of the most common hereditary hematological alterations. in brazil, the frequency of the sickle cell trait (hbas) varies from 2% to 8%. thus, there is an estimate of more than two million carriers of the hbas sickle cell trait in brazil. different to homozygous...
hemoglobin S词源英文解释 The first known use of hemoglobin S was in 1954 hemoglobin S医学词典英英释义 hemoglobin Snoun an abnormal hemoglobin occurring in the red blood cells in sickle cell anemia and sickle-cell trait and differing from hemoglobin A in having a valine residue substituted for the...
he·mo·glo·bin S [MIM*141900] an abnormal Hb with substitution of a valyl residue for a glutamyl residue at the sixth position of the β chain; the formula is α2Aβ2S, or, more specifically, α2Aβ26Glu→Val. Heterozygous state: sickle cell trait, no anemia, Hb S 20-45% of ...
Materials and Methods: Three groups were studied and consisted in 31 controls (group AA), 26 sickle cell trait (group AS) and 29 SCD patients (group SS) at steady state. Hemoglobin phenotype was assessed by combination of cation-exchange high performance chromatography (beta-thal short program ...
Analysis of the data obtained did not show any statistically significant protective advantage for sickle cell trait against Burkitt's lymphoma. Hemoglobin C trait appeared to offer a slight protective advantage (p less than 0.1), but this did not reach statistical significance. These results do not...
Sickle cell disease is fully expressed in individuals that inherit a defective hemoglobin gene from each parent. The individual that inherits only one defective gene has much milder symptoms or no symptoms and is considered to have sickle cell trait, not sickle cell disease. What Is Thalassemia?