N. M. Nseka心血管病(英文)Lepira FB, Mukendi TK, Mbutiwi FIN, Makulo JR, Sumaili EK, Kayembe PK, et al. Sickle cell trait, hemoglobin levels and anemia among black patients with predialysis chronic kidney disease: a post hoc analysis. World J Cardiovasc Dis. 2016;6:258....
Sickle Cell Disease (Clinical) Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal Hb molecule (Hb S) transforms RBCs into sickle-shaped cells, resulting in chronic anemia, vasoocclusive episodes, pain, and organ damage. Sickle cell trait, which is the heterozygous...
There is also a high prevalence of an independent Swiss type hereditary persistence of fetal hemoglobin (HPFH) determinant active in both the sickle cell trait and in sickle cell disease. 展开 关键词: Humans Anemia, Sickle Cell Thalassemia Fetal Hemoglobin Globins Haplotypes Homozygote Adolescent ...
Sickle Cell Trait(Hemoglobin AS) The prevalence of sickle cell trait varies throughout the world; in the United States the incidence is 7–10% of African Americans. Because all state newborn screening programs include sickle cell disease, for most children, sickle cell trait is first identified...
Related to sickle cell:sickle cell trait,Sickle cell crisis n. An abnormal, crescent-shaped red blood cell that results from a single change in the amino acid sequence of the cell's hemoglobin, which causes the cell to contort, especially under low-oxygen conditions. ...
The highest prevalence of sickle-cell trait (SCT) in Africa occurs between the latitudes of 15° North and 20° south, where the prevalence ranges between 10% and 40% of the population (Agasa et al., 2010). In 2010, Rawezula reported results of a study of records of over 2000 newborns...
Inheritance of only one copy causes sickle cell trait, which usually does not cause symptoms, but places individuals at risk of passing the mutation on to their offspring. Sickle cell anemia is also sometimes referred to as a Mendelian disease because of the way it is inherited, and as such...
C. Protection afforded by sickle-cell trait against subtertian malarial infection. BMJ 1, 290–294 (1954). CAS PubMed PubMed Central Google Scholar Luzzatto, L. Sickle cell anaemia and malaria. Mediterr. J. Hematol. Infect. Dis. 4, e2012065 (2012). PubMed PubMed Central Google ...
Questis a leading name in medical testing. The company’s Sickle Cell Trait Screen Test with Reflex is intended to measure levels of abnormal hemoglobin and detect sickle cell disease and other conditions caused by gene mutation. You’re a good candidate for the test if a parent or other fam...
The term sickle cell trait refers to the carrier state for SCD; it is the most benign type of SCD, in that less than 50% of the hemoglobin within an erythrocyte is HbS One Parent with the trait 50% - normal 50% - trait Both Parents with the trait ...