How to use the hematopoietic stem cells and the cells for treating diseases of neovascular ocularIsolated, mammalian, bone marrow-derived, lineage negative hematopoietic stem cell populations (Lin- HSC) contain endothelial progenitor cells (EPC) capable of forming retinal blood vessels. At least about...
The fascinating plasticity of adult hematopoietic stem cells gives them the ability to act either as stem cells or to differentiate to become another tissue, which can be used to reprogram the fate of a cell [17]. This can be a rationale for treating COVID infection. View chapterExplore ...
Chemomobilization is especially useful in those patients with a high risk of stem cell mobilization failure as it can increase the PBSC yield while concomitantly decreasing the MM tumor burden. However, in a non-randomized assessment, this has not yielded superior OS outcomes compared to ...
Stem cell transplant is a highly effective way of reducing inflammation, including new relapses and new MRI lesions and it’s quite effective, especially for younger relapsing patients. It is a very involved procedure, which takes anywhere from around 2 weeks for the procedure. In a...
Hematopoietic cell transplantation (HCT) aims to replace the host's malignant, absent, or genetically defective cells through stable engraftment of donor stem cells after partial or complete ablation of the recipient's bone marrow by using a number of modalities, including radiation, chemotherapy and...
Abstract Importance Hematopoietic stem cell transplantation (HSCT) represents a potentially useful approach to slow or prevent progressive disability in relapsing-remitting multiple sclerosis (MS). Objective To compare the effect of nonmyeloablative HSCT vs disease-modifying therapy (DMT) on disease progress...
Given the massive rate of hematopoi- etic cell turnover (e.g., daily turnover in the human body is estimated to be 1 × 1012 cells [9]), there are not nearly enough HSCs to continuously replenish mature blood cells Cell Research | www.cell-research.com Hematopoietic stem cell (HSC) ...
Pyrimido[4,5-b]indole derivatives are provided. These compounds are useful to expand hematopoietic stem cell populations, particularly, human hematopoietic stem cell populations. Th
A bank of fetal liver HSC will prove useful in treating a variety of genetic diseases before birth by in utero HSC transplantation. 展开 关键词: Fetal liver transplantation hematopoietic stem cell in utero transplantation DOI: 10.1016/S0022-3468(98)90470-5 被引量: 180 ...
In addition, enriching pluripotent stem cells should greatly enhance the treatment of immunodeficency disorders. Furthermore, the effectiveness of the treatment of blood diseases by ex vivo gene therapy, e.g., treating sickle cell anemia or thalassemia, could also be substantially enhanced. ...