This study describes a facile one-step method to synthesize stable AuNPs loaded with combination of two anticancer therapeutics, -bleomycin and doxorubicin. Anticancer activities, cytotoxicity, uptake and intracellular localization of the AuNPs were demonstrated in HeLa cells. We show that the therapeutic...
HeLa cells refer to a line of cells belonging to a strain that has been continuously cultured since 1951 and were the only cells to survive in vitro.
Hochest 33342 staining results showed QW-83 could obviously induce cells apoptosis and nuclear pyknosis. Flow cytometry showed QW-83 could increase apoptosis rate in concentration-dependent manner, being 16.89%-62.56%. RT-PCR showed mRNA expression of P53, Bax, Caspase-3, Casepase-8 and Case...
Abstract In order to investigate the growth inhibition effect of thymosin alpha 1 (Tai ) on tumor cells , this study detected the effect of Tai on the growth and proliferation of Hela cells of cervical cancer in vitro. The morphology of ...
【关键词】 Hela细胞;蛋白质组;2 DE;MALDIO TOF MS;肽质量指纹图谱 【中图分类号】 Q503 IdentificationofProteinsfromHelaCellsbyTwo DimensionalElectrophoresis andPeptideMassFingerprinting 1 2 1,3 1 1 1,3 HUJ 下载文档 收藏 分享赏 0
The immortal HeLa cells case is an intriguing example of bio-objectification processes with great scientific, social, and symbolic impacts. These cells generate questions about representation, significance, and value of the exceptional, variety, individuality, and property. Of frightening (a lethal cance...
HeLa cellscytotoxicityQSARThe study of interactions of low frequency and intensity electromagnetic fields (100 Hz and 5.5 mT of LFI- EMF) with some membrane bound and intracellular enzymatic biomolecules of HeLa cells has revealed an enhancement of membranary Na+-K+-ATP-ase, intracell LDH, SOD ...
In this study, its pro-apoptotic and anti-apoptotic activities on human cervical cancer (HeLa) cells in vitro were investigated. Silymarin induced HeLa cell death through both apoptotic and necrotic pathways. At low doses (below 80 mol l 1), it induced cell apoptosis, but caused necrosis at...
“Johns Hopkins hasnever sold or profited from the discovery or distribution of the HeLa cells and does not own the rights to the HeLa cell line,” the spokeswoman said. Scientists have improved ethical rules in the wake of public attention about the Lacks case. ...
This study has found that in HeLa cells, with increasing of the administered concentration of Bortezomib, MMP2 and MMP9 expression have been significantly inhibited. In summary, bortezomib can inhibit the expression of MMP2 and MMP9 by blocking Akt/mTOR signaling pathway. And then it can ...