Henrietta's cells were the first immortal human cells ever grown in culture.They were essential to developing the polio vaccine. ... Many scientific landmarks since then have used her cells, including cloning, gene mapping and in vitro fertilization. Who profited from HeLa cells? “Johns Hopki...
BrinkmanAB,eta1.Quantitativecomparisonofgenome—wideDNAmethylationmappingtechnologies[J].NatureBio-technology,2010,28(10):1106—1114.[21]SandovalJ,HeynH,MoranS,etat.ValidationofaDNAmethylationmicroarrayfor450,000CpGsitesinthehumangenome[J].Epigeneiics:O[ficLMJournaloftheDNAMethylafion,~dety,2011,6(6)...
Studies of gene transcription of the infected cell have shown altered transcription of many host cell genes, indicating a transcriptional response of the host cell to the infection. We here describe that infection of HeLa cells with C. trachomatis as well as infection of murine cells with C. ...
were taken up by HeLa cells in a time- and temperature-dependent fashion and did not affect the HeLa cell growth rate, evidence that the SWNTs inside cells were not toxic under these conditions [19]. This work also demonstrated that our dispersion preparation ...
Using this new pipeline, we sequenced single-cell tran- scriptomes of 40 HeLa S3 cells, and demonstrated exten- sive heterogeneity of this virus-infected cell line in gene expression, alternative splicing, and fusion. Furthermore, we also found a set of genes which are potential...
www.nature.com/scientificreports OPEN received: 19 May 2016 accepted: 29 June 2016 Published: 25 July 2016 Lysine Acetylation and Succinylation in HeLa Cells and their Essential Roles in Response to UV-induced Stress Hong Xu1,*, Xuanyi Chen1,*, Xiaoli Xu1,*, Rongyi Shi1, Shasha...
In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, such as base modification, single- or double- strand breaks, and inter-strand cross-links1,2. The biological consequences of DNA damage depend on the type of lesions...
In order to achieve a greater understanding of NMD regulated gene expression we used 2D-DiGE proteomics technology to examine the changes in protein expression induced in HeLa cells by UPF1 knockdown. QPCR based validation of the corresponding mRNAs, in response to both UPF1 knockdown and cyclohexi...
DNA Replication Initiates Non-Randomly at Multiple Sites Near the c-myc Gene in HeLa Cells The origin of replication of the c-myc gene in HeLa cells was previously identified at low resolution within 3.5 kb 5' to the P1 promoter, based on replica... SE Waltz,AA Trivedi,L Michael - 《...
The blockage of cells in metaphase is immediate at all co... HM Meisner,L Sorensen - 《Experimental Cell Research》 被引量: 48发表: 1966年 Transforming growth factor type β3 maps to human chromosome 14, region q23-q24 Chromosomal localization of the TGF-beta 3 gene was performed by ...