Review of the activation of TGF-beta in immunity. J Leukoc Biol. 85(1):29-33. 3. Battle E. & Massagué J., 2019. Transforming Growth Factor-beta Signaling in Immunity and Cancer. Immunity. 50(4):924. Back to the top FAQ Cell Lines Any questions about our cell lines ? Visit ...
HEK-Dual™ hTLR3 cells were engineered from HEK-Dual™ cells, a human embryonic kidney HEK293-derived cell line, to study the human Toll-like receptor 3 (hTLR3)-dependent NF-κB and IRF responses. This important pattern recognition receptor (PRR) recognizes double-stranded (ds)RNA, a ...
one of the biggest hurdles has been that HEK293 cells tend to aggregate in suspension culture, especially at high cell density. Cell clumping in suspension culture is extremely detrimental to a growing population since it restricts the cells inside of the clump from access to sufcient oxygen and...
Within the biopharmaceuticals market, the most utilized model systems for protein production are, by far, mammalian cell lines. Although CHO cells make up the largest portion of these cell lines, some proteins still require a human intracellular environment for proper folding, post-translational modif...
transcriptomic and metabolic gene analysis of six of the most widely used HEK293 cell lines. Changes in gene copy and expression between industrial progeny cell lines and the original HEK293 were associated with cellular component organization, cell motility and cell adhesion. Changes in gene expressi...
Cell Type Cancer Cells and Cell Lines, Hematopoietic Stem and Progenitor Cells, Mesoderm, PSC-Derived, Neurons Species Human Area of Interest Neuroscience, Stem Cell Biology Purity ≥ 94% View More Data Figures Figure 1.Biological Activity and Molecular Mass of Human Recombinant G-CSF (HEK293-exp...
Growth kinetics and VLP production of HEK293 cells transfected with Gag::eGFP plasmid carrying the shRNAs targeting DNA-PKcs, ATR, ATM, and PDEδ. a. Viable cell density (solid lines) and viability (dotted lines) of the different conditions along the studied time course (n = 3). b....
1 pouch ofHEK-Blue™ Detection(cell culture medium for real-time detection of SEAP) Shipped on dry ice (Europe, USA, Canada, and some areas in Asia) Back to the top FAQ Cell Lines Any questions about our cell lines ?Visit our frequently asked questions page ...
2.1. Cell Line For all experiments, we used the commercial HEK293T cell line (https://www.thermofisher.com/br/en/home/technical-resources/cell-lines/2/cell-lines-detail-153.html, accessed on 15 February 2021). Cells were grown in DMEM medium (Gibco) supplemented with 10% fetal bovine se...
HEK293 cells: cell variants from a common origin The origin of HEK293 cells dates back to 1973 and since then multiple variant HEK293 cell lines have been derived and utilised for distinct purposes. At the start of this review, we would direct the reader to an excellent systems biology stud...