We studied two related patients from a large consanguineous family from Colombia (Fig.1a; see the ‘Extended case reports for P1 and P2’ section of theMethods). P1 is a 28-year-old woman. She was diagnosed with pulmonary TB at the age of 19 years, presenting with dry cough, pleuritic ...
For insulin secretion experiments in INS-1 cells, treatment groups were randomly assigned to different wells within each 24-well plate. Pancreatic islets were isolated from fed, weight-matched Wistar or GK rats chosen at random. Then, pancreatic islets were randomly assigned to different treatments....
n = 6 mice per group. d Daily food intake during 6-day period in mice housed at 23 or 6 °C. Before exposure to cold mice were fed for 8 weeks with chow diet and housed at 23 °C. n = 5 mice per group. e Weight loss in mice housed at 6 °C for 15 days...
In the present study, a total of 12 12-month-old free-range yaks with similar blood profile and weight (6 healthy and 6 diarrheic) were selected for sample collection from Qinghai Province, China, including 3 male and female yaks in each group. The diarrheic yaks were diagnosed by professio...
Fig. 6 Lactobacillus-derived L-Orn promotes resistance to DSS-mediated colitis. a Experimental design for B–G. b, c, Survival rate (b) and body weight and the disease activity score (c) were monitored after the start of DSS. Wild-type (WT) mice with (L-Orn) or without (Vehicle) ...
Characteristics LRC Group LRE Group Age (year) Sex (male/female) Height (cm) Weight (kg) Body mass index (kg/m2) 103 ± 3 11/19 145.9 ± 10.6 43.1 ± 10.0 20.0 ± 2.8 63 ± 3 12/19 153.7 ± 7.2 49.4 ± 9.4 20.8 ± 2.9 Values are means ± standard deviation (SD). LRC, ...
The inclusion criteria for this research were: male and female participants between 13 and 16 years old who had submitted the signed informed consent by their parents/guardians. Related to their health status, participants in the present investigation were those subjects who, due to their state of...
For the analysis of data for this project, we did not separate results by gender. Data from two subjects were unable to be processed and were not included in analyses (one male, one female). Table 1. Participant characteristics. Sex Age (y) Height (cm) Weight (kg) BMI (kg/m2) ...
Body mass index (BMI) was expressed as weight (kilograms) divided by height2·(meters)2. Blood samples were collected between 8 and 9 a.m. after overnight fasting. DNA was extracted by the Miller technique [31] and was stored at –80 ◦C until further use. For the MuTHER study, 8...
Postmenopausal healthy female volunteers were genotyped for the polymorphisms Xbal and PvuII of ESR1 and the polymorphism rs1256030 of ESR2. The effect of these polymorphisms on the response to the facial emotion recognition of the emotions happiness, sadness, disgust, anger, surprise, and fear ...