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Perilipin 5 overexpression in BAT improves glucose tolerance and insulin sensitivity at room temperature with reduction in weight only during cold exposure Given our data that PLIN5 promotes mitochondrial function in a brown adipocyte cell line34, we asked whether PLIN5 gain-of-function in BATiPLIN...
a, Pedigree of two related kindreds showing familial segregation of the c.190_191ins20 (p.P64Lfs*13)TNFallele. Each generation is designated by a Roman numeral. Male and female individuals are represented by squares and circles, respectively. The filled boxes indicate individuals affected by TB...
We performed a monozygotic (MZ) cotwin–control study using the MZ twin pair difference in bone mineral density (BMD) to assess the relationship between body composition and BMD at weight-bearing sites. This study controlled for common genetic factors and applied only to environmental factors...
Waterhouse J et al (2001) Temperature profiles, and the effect of sleep on them, in relation to morningness-eveningness in healthy female subjects. Chronobiol Int 18:227-247Waterhouse, J., Folkhard, S., Van Dongen, H., Minors, D., Owens, D., Kerkhof, G., Weinert, D., Nevill...
We all know that awful feeling when we’re sleep-deprived. It’s hard to focus, our bodies feel depleted, and our moods suffer greatly. But did you know that a lack of proper sleep can lead to weight gain, reduce productivity, and increase your risk for heart attack and stroke? Priorit...
Methods: FAs compositions and inflammation statuses (based on serum C-reactive protein (CRP) levels) were studied in serum samples obtained from 102 female volunteers (divided into four groups: vegans, vegetarians, pescatarians, and omnivores). The quality of the volunteers’ diets was assessed ...
Donepezil and memantine are the most common drugs used for Alzheimer’s disease. Their low effectiveness could partly be explained by genetic factors. Thus, we aim to identify Single Nucleotide Polymorphisms (SNPs) associated with pharmacokinetics, pharm
In particular, the effect of ResoK remains to be evaluated in pancreatic islets prepared from female rats in order to determine whether its pharmacological profile is preserved regardless of sex differences. In the setting of metabolic disorders, the multi-target nature of flavonoids (Carullo et al...
In the present study, a total of 12 12-month-old free-range yaks with similar blood profile and weight (6 healthy and 6 diarrheic) were selected for sample collection from Qinghai Province, China, including 3 male and female yaks in each group. The diarrheic yaks were diagnosed by professio...