Interestingly, the valency of the inhibitor had a dramatic effect on the mechanism of aggregation, influencing both the kinetics of aggregation and the stability of intermediate protein complexes. In addition, structural studies employing AFM have revealed that a divalent inhibitor induced head-to-head...
Cyrene as a bio-based solvent for HATU mediated amide coupling 1Kirsty L. Wilson aJane Murray bCraig Jamieson aAllan J.B. Watson c Person EnvelopeOrganic & Biomolecular Chemistry