内容提示: weight.(2,3)A case of allergic contact dermatitis, attributed to theuse of maltol in a lip ointment, has been reported.(4)LD50(chicken, oral): 3.72g/kg(5)LD50(guinea pig, oral): 1.41g/kgLD50(mouse, oral): 0.85g/kgLD50(mouse, SC): 0.82g/kgLD50(rabbit, oral): 1.62g...
Povidone has been used in pharmaceutical formulations for many years, being first used in the 1940s as a plasma expander, although it has now been superseded for this purpose by dextran. (8) SEM4: Excipient: povidone K-26/28 (Plasdone K-26/28); manufacturer: ISP; lot no.: 82A-2; ma...
excipientspharmaceutical药学辅料ethylparabenfructose LD 50 (mouse,IP):0.52g/kg (12) LD 50 (mouse,oral):3.0g/kg 15HandlingPrecautions Observenormalprecautionsappropriatetothecircumstancesand quantityofmaterialhandled.Ethylparabenmaybeirritanttothe skin,eyes,andmucousmembranes,andshouldbehandledinawell ventilated...
本数据库为药用辅料手册(Handbook of Pharmaceutical Excipients)第6版,为目前最权威的药用辅料专著。可在线查询各辅料专论全文。
Pharmaceutical excipients. Adverse effects associated with inactive ingredients in drug products (Part I). Excipient reactions have resulted from the use of clearly toxic substances (e.g. diethyleneglycol), the use of certain excipients in a susceptible group (e... LK Golightly,SS Smolinske,ML ...
When used for the manufacture of pharmaceutical/ biotechnological products, most raw materials are not sterile when received by the pharmaceutical manufacturer. Regardless, the materials should be processed under CGMPs wherein their microbiological bioburden can be maintained within predetermined limits. When...
Handbook of Pharmaceutical Granulation Technology
Handbook of Pharmaceutical Excipients – 7th Edition InteractionsPipeline Rules of Thumb HandbookMartindaleExcipient Development for Pharmaceutical, Biotechnology, and Drug Delivery SystemsHandbook of Pharmaceutical ... R Rowe - 《Pharmaceutical Development & Technology》 被引量: 0发表: 2013年 Pipeline Rules...
An understanding of polymorphism (or pseudopolymorphism) in magnesium stearate and the impact on tablet lubrication process and drug dissolution would provide a valuable tool to pharmaceutical scientists during excipient selection process for new product development and even during reformulation of existing ...
When used for the manufacture of pharmaceutical/ biotechnological products, most raw materials are not sterile when received by the pharmaceutical manufacturer. Regardless, the materials should be processed under CGMPs wherein their microbiological bioburden can be maintained within predetermined limits. When...