CATALYSISCATALYSTSChiral halogen-bonding catalysts have emerged as a new approach towards asymmetric catalysis, but enantioselectivities have thus far remained low. Now, fine-tuning the substrate–catalyst halogen–halogen interactions is shown to significantly enhance enantioselectivity for a model anion-...
Halogen bonding (XB) is the non-covalent interaction that occurs between a halogen atom (Lewis acid) and a Lewis base. Although halogens are involved in other types of bonding (e.g. covalent), halogen bonding specifically refers to when the halogen acts as an electrophilic species. Bonding F...
The development of noncovalent halogen bonding (XB) catalysis is rapidly gaining traction, as isolated reports documented better performance than the well-established hydrogen bonding thiourea catalysis. However, convincing cases allowing XB activation to be competitive in challenging bond formations are lack...
The same holds true for halogen bonding; in spite of sharing several characteris- tics with hydrogen bonding, only a handful of examples have appeared in the last years. Similarly to anion receptors based on halogen-bond donors, a single example for catalysis with halogen bonding appeared before...
R. Acid–base catalysis in glycosidations: a nature derived alternative to the generally employed methodology. Acc. Chem. Res. 50, 1171–1183 (2017). Article CAS PubMed Google Scholar Seeberger, P. H. The logic of automated glycan assembly. Acc. Chem. Res. 48, 1450–1463 (2015). ...
Nonヽovalent molecular interactions on the basis of halogen and chalcogen bonding represent a promising, powerful catalytic activation mode. However, these "unusual" nonヽovalent interactions are typically employed in the solid state and scarcely exploited in catalysis. In recent years, an increased ...
The great potential of Halogen Bonding (XB), namely any noncovalent interaction involving halogens as electron acceptors, in the design of new and high-value functional materials is now emerging clearly. This Highlight will give a detailed overview on the energetic and geometric features of XB, ...
We first provide a detailed exposition of the fundamental redox mechanisms, thermodynamics, conversion and catalysis chemistry, and mass or electron transfer modes involved in HSCBs. We conclude with a perspective on the challenges faced by the community and opportunities towards practical applications ...
Here, we show the first instance of halogen bonding having a direct influence on local dynamical processes, with the halogen bond donor acting as a dynamics catalyst superior to the hydrogen bond. In this context, dynamics catalysis refers to the reduction of the energy barrier associated with a...
In contrast, the use of halogen bonding to trigger supramolecular gel formation in a two-component gel (‘co-gel’) is essentially unexplored, and forms the basis for this study. Here, we show that halogen bonding between a pyridyl substituent in a bis(pyridyl urea) and 1,4-diiodo...