因此,需要进一步在分子水平上确定GBM中的T细胞类群,来指导GBM的免疫疗法。 近日,哈佛医学院Allegra A. Petti和Gavin P. Dunn、布列根和妇女医院Tanner Johanns联合在Cancer discovery期刊上发表题为Glioblastoma-infiltrating CD8+T cells ...
因此,需要进一步在分子水平上确定GBM中的T细胞类群,来指导GBM的免疫疗法。 近日,哈佛医学院Allegra A. Petti和Gavin P. Dunn、布列根和妇女医院Tanner Johanns联合在Cancer discovery期刊上发表题为Glioblastoma-infiltrating CD8+T cells are predominantly a clonally expanded GZMK+effector population的研究论文,使用多组...
Dunn、布列根和妇女医院Tanner Johanns联合在Cancer discovery期刊上发表题为Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population的研究论文,使用多组学方法对脑胶质瘤患者的T细胞进行测序,发现典型的T细胞耗竭标志在高级别胶质瘤(HGG)的TIL中弱表达。值得注意的是,在...
CD8 T cellsgranzyme Ksingle-cell RNA-sequencingsingle-cell ATAC-sequencingsingle-cell TCR-sequencingsingle-cell BCR-sequencingCITE-seqA systematic analysis of the ageing immune system of the mouse revealed the emergence of a novel T cell subset that displays markers of exhaustion. A similar T ...
近日,哈佛医学院Allegra A. Petti和Gavin P. Dunn、布列根和妇女医院Tanner Johanns联合在Cancer discovery期刊上发表题为Glioblastoma-infiltrating CD8+T cells are predominantly a clonally expanded GZMK+effector population的研究论文,...
GZMK high CD8 + T effector memory cells are associated with CD15 high neutrophil abundance in early-stage colorectal tumors and predict poor clinical outcomedoi:10.1101/2021.12.14.472046Silvia TibertiCarlotta CatozziCaterina ScirgoleaTERESA o MANZO...