Briefings in Functional GenomicsCani P.D. Gut microbiota and obesity: Lessons from the microbiome. Brief. Funct. Genom. 2013; 12 :381–387. doi: 10.1093/bfgp/elt014. [ Cross Ref ]Cani PD. Gut microbiota and obesity: lessons from the microbiome. Brief Funct Genomics 2013;12:381-7....
The influence of the gut microbiota in human health and disease has been revealed in the recent years. Particularly, the use of germ-free animals and microbiota transplant showed that the gut microbiota may play a causal role in the development of obesity and associated metabolic disorders, and ...
Obesity is caused by a long-term difference between energy intake and expenditure — an imbalance that is seemingly easily restored by increasing exercise and reducing caloric consumption. However, as simple as this solution appears, for many people, los
The gut microbiota refers to the trillions of microorganisms residing in the intestine and is integral in multiple physiological processes of the host. Recent research has shown that gut bacteria play a role in metabolic disorders such as obesity, diabetes, and cardiovascular diseases. The mechanisms...
原名:Phlorizin ameliorates obesity-associated endotoxemiaand insulin resistance in high-fat diet-fed mice by targeting the gutmicrobiota and intestinal barrier integrity 译名:根皮苷通过干预肥胖小鼠的肠道菌群和肠道屏障完整性来改善肥胖相关的内毒素血症和胰岛素抵抗 ...
Inflammation is a common feature of both obesity and cancer; however, the origin of this inflammation has been largely debated. Over the past decade, growing evidence has shown that the composition of the gut microbiota and its activity might be associated not only with the onset of inflammation...
Zhao L. The gut microbiota and obesity: from correlation to causality. Nat Rev Microbiol. 2013;11:639–47.PubMed 26. Hildebrandt MA, Hoffmann C, Sherrill-Mix SA, Keilbaugh SA, Hamady M, Chen Y-Y, et al. High-fat diet determines the composition of the murine gut microbiome independently...
The central role of the intestinal microbiota in the progression and, equally, prevention of metabolic dysfunction is becoming abundantly apparent. The symbiotic relationship between intestinal microbiota and host ensures appropriate development of the metabolic system in humans. However, disturbances in comp...
Gut microbiota: Microbiota fasting-related changes ameliorate cognitive decline in obesity and boost ex vivo microglial function through the gut-brain axis 7 May 2025 Commentary: When getting reactive becomes the nORM: the emerging roles of proinflammatory cholangiokines ...
越来越多的研究表明小肽可以有效影响机体代谢以及调节肠道菌群结构，但目前能够减重的可口服多肽类药物依然缺乏。Gut 期刊发表的来自中国科学院北京生命科学研究院赵方庆团队与陆军军医大学魏泓团队的题为“A novel peptide protects against diet-induced obesity by suppressing appetite and modulating the gut microbiota”...