Overweight, obesity, undernutrition and their respective sequelae have devastating tolls on personal and public health worldwide. Traditional approaches for treating these conditions with diet, exercise, drugs and/or surgery have shown varying degrees of success, creating an urgent need for new solutions...
In 2007, Indi Trehan was approached by a Malawian woman whose two children were severely malnourished. Trehan, a paediatrician from Washington University in St Louis, had seen many such cases. Malawi has one of the highest rates of child mortality in the
The role of the gut microbiota in energy metabolism of the host has been established, both in overweight/obesity, as well as in undernutrition/stunting. Dysbiosis of the gut microbiota may predispose to stunting. The aim of this study was to compare the gut microbiota c...
This influence is evidenced by observations that abnormal gut microbiota composition is associated with undernutrition/stunting [3], obesity [4], and sarcopenia [5], which can be partially alleviated through fecal microbiota transplantation from healthy individuals [3,4,5,6]. The phenomenon that ...
In this review, the role of the gut microbiota in energy harvest and fat storage is explored, as well as differences in the microbiota in obesity and undernutrition. 展开 关键词: microbiome metagenome obesity malnutrition absorption energy metabolism ...
et al. Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition. Science 351, 854–857 (2016). Article ADS CAS PubMed Google Scholar Liu, Y.-W. et al. Psychotropic effects of Lactobacillus plantarum PS128 in early life-stressed and naïve adult mice. ...
small intestinal microbiota microbiome western diet lipid digestion and absorption obesity malnutrition undernutrition gnotobiotic mice host-microbe interactions gut microbes microbiome intervention; 6.Epithelial maturity influences EPEC-induced desmosomal alterations ...
The goal of this special focus issue was to review the role of diet in regulating the composition and function of the gut microbiota across the lifespan, from pregnancy to old age. Overall dietary patterns, as well as perturbations such as undernutrition and obesity, as well as the effects ...
R. et al. Sialylated milk oligosaccharides promote microbiota-dependent growth in models of infant undernutrition. Cell 164, 859–871 (2016). Article CAS PubMed PubMed Central Google Scholar Laursen, M. F., Bahl, M. I., Michaelsen, K. F. & Licht, T. R. First foods and gut microbes...
microbiota-host interactions still remains elusive. Recent reports have suggested that changes in m6A levels are associated with inflammatory states14,34and very recently, the presence of a microbiota has been suggested to induce changes in epitranscriptomic profiles in the brain, and several other ...