Research about the role of gut microbiome in colorectal cancer (CRC) is a newly emerging field of study. Gut microbiota modulation, with the aim to reverse established microbial dysbiosis, is a novel strategy for prevention and treatment of CRC. Different strategies including probiotics, prebiotics,...
The invasion by pathogens or toxins is bad enough, but the body’s reaction may be worse. When the immune system counterattacks, there is plenty of collateral damage. Immune cells are not subtle. If they target a microbe inside a nerve cell, they may kill the cell along with the...
2019年,发表在Microbiome题为“Reproducible changes in the gut microbiome suggest a shift in microbial and host metabolism during spaceflight”的研究,文章借助16S rRNA扩增子和NASA基因实验室数据库中的转录组数据,对在ISS上飞行37天的小鼠进行...
Gut microbiome and depression: what we know and what we need to know. Rev Neurosci. 2018;29:629–43. Article PubMed Google Scholar Zheng P, Zeng B, Zhou C, Liu M, Fang Z, Xu X, et al. Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the ...
The gut microbiome regulates the increases in depressive-type behaviors and in inflammatory processes in the ventral hippocampus of stress vulnerable rats. Mol Psychiatry. 2019. https://doi.org/10.1038/s41380-019-0380-x [Epub ahead of print]. Zheng P, Zeng B, Zhou C, Liu M, Fang Z, Xu...
even essential to our health. Our guts are said to be full of “friendly” bacteria and other microorganisms that do us favours in return for us giving them a cosy home. That is true to some extent, but new research ...
An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 2006;444:1027–131. doi:10.1038/nature05414. Article PubMed Google Scholar Peterson DA, Frank DN, Pace NR, Gordon JI. Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell ...
habitat than for other factors. In addition, the fish gut microbiome in a PCoA plot clustered separately from those of other vertebrates, such as mammals, reptiles, and birds. Our findings improve our understanding of ...
weight loss, namely LED complete meal replacement. The discrepancy may perhaps arise from small differences in macro and micronutrient composition, compliance to the LED, or more likely differences in microbiome methodologies which may be exacerbated in these studies of very small sample size [12,22...
To explore signatures of the gut microbiome in healthy or tumour samples, we identified 130,715 genes that displayed significant abundance differences in any two of the three groups (Kruskal–Wallis test, Benjamin–Hochberg q-valueo0.1; Fig. 3). None of the available phenotypes other than ...