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The effect of microbes on their human host is often mediated through changes in metabolite concentrations. As such, multiple tools have been proposed to predict metabolite concentrations from microbial taxa frequencies. Such tools typically fail to captu
Human gut microbiota directly influences health and provides an extra means of adaptive potential to different lifestyles. To explore variation in gut microbiota and to understand how these bacteria may have co-evolved with humans, here we investigate the phylogenetic diversity and metabolite production ...
fungi, phages/viruses, archaea, and protozoa are also important members of the gut microbiota. Exploration of taxonomic compositions beyond bacteria as well as an understanding of the interaction between the bacteriome with the other members is limited using 16S rDNA sequencing. Here, we developed a...
(PC1) values, and shown in thebox plots above. **Pvalue <0.001, Wilcoxon rank sum test.bThe average abundance of KEGG modules differentially enriched in control, pHTN, and HTN gut microbiome. Twenty nine modules enriched in control, and 11 modules overrepresented in both pHTN and HTN are...
Children with cancer receiving chemotherapy commonly report a cluster of psychoneurological symptoms (PNS), including pain, fatigue, anxiety, depression, and cognitive dysfunction. The role of the gut microbiome and its functional metabolites in PNS is r
“typical” microbiome of the elderly, but the trends are in the very direction Metchnikoff described: a shift from the fermentation of fiber to the putrefaction of protein. This deviation from good bugs to bad is accompanied by an increase in gut leakiness, the spillage of bacterial toxins ...
Posted in Animal experiments, Animal microbiome, Fungi, Human gut, Human oral, Human reproductive or urinary, Human respiratory, Human skin, Metabolomics, Metagenomics & Bioinformatics, Plant Root Soil microbiome, Pregnancy and birth, Techniques | Leave a comment October 4, 2024 Posted on October...
Alzheimer’s disease (AD) is the most common form of dementia. However, the etiopathogenesis of this devastating disease is not fully understood. Recent studies in rodents suggest that alterations in the gut microbiome may contribute to amyloid depositio
(Fig.6), which represents the pathogenic agent integrated within its biotic environment, was established and applied to multiple pathosystems [141]. This approach suggests that microbial diversity is a key factor in preventing diseases in plants [23] as well as in the human gut [142]. Despite...